SARS CoV-2 coronavirus / Covid-19 (No tin foil hat silliness please)
- Thread starter Don't Kill Bill
- Start date
I'll need that translated
According to the paper Epsilon variant is showing higher resistance to vaccines due to mutations in the spike protein. However, according to this , it actually is deescalated in concern, and vaccines seem to work against it.
This is not my field, I had a microbiologist summarise the paper for me.
@WI_Red can probably pitch in here as well.
Thank you.
In my dad's case (still awaiting PCR result) - he has a bad cough, but his SATs are currently fine, so praying it's not Covid, and especially not Delta. In his age, condition, and with a lifetime of smoking, he's ill prepared for it.
@WI_Red is a bottle and a half of wine in with the missus and will need to read the papers tomorrow.
Dude why you even replying
Dude why you even replying
We were heading outside to finish bottle 2 when I saw the message.
she is also a microbiologist and we were just discussing the delta variant (I know, we have amazing sexy talk) so replying was on topic.
Thanks. Mere mortals like me have no idea
Interesting update from someone who's usually a good source of balanced but up to date information, a London ICU consultant and research professor.
Broadly as anticipated, hospitalisations rising. ICUs are getting busy, but mostly supporting people with additional oxygen rather than ventilators. They're currently expecting patient numbers to peak in August, and are hoping that they won't all arrive at once.
Broadly as anticipated, hospitalisations rising. ICUs are getting busy, but mostly supporting people with additional oxygen rather than ventilators. They're currently expecting patient numbers to peak in August, and are hoping that they won't all arrive at once.
Covid too tough for Tough Mudder. This year's race has been cancelled.
https://www.theguardian.com/uk-news...cotland-cancelled-at-last-minute-due-to-covid
Understandably the organisers aren't impressed by the late cancellation especially given:
“The irony is not lost on us that just this past weekend, almost 16,000 rugby fans gathered together in Murrayfield, just 10 minutes up the road."
And the big crowds at Wimbledon and Wembley this week.
https://www.theguardian.com/uk-news...cotland-cancelled-at-last-minute-due-to-covid
Understandably the organisers aren't impressed by the late cancellation especially given:
“The irony is not lost on us that just this past weekend, almost 16,000 rugby fans gathered together in Murrayfield, just 10 minutes up the road."
And the big crowds at Wimbledon and Wembley this week.
Yeah that’s something I don’t get, small gatherings banned but for example Ascot was allowed. Lots of toffs dressed up. Hmmm
ok, so after giving the paper a read I think I understand. The epsilon variant is more resistant to both vaccination induced antibodies and infection generated antibodies. Interestingly, the vaccine antibodies are still more potent. My guess is because they are monoclonals targeted at specific, highly conserved, regions of the S protein. However, I do not think that these mutations confer any significant increase in transmissibility.
essentially this variant is starting the “infect the humans race” late and does not have an advantage in transmission to give it a boost. It does have an advantage in overcoming an antibody mediated defense, but that appears to not be great great enough to be able to make a dent in the vaccinated population, and more established variants still dominate the unvaccinated population. While the percent of the infections for epsilon variant remains low the CDC will keep tracking it, but will likely keep it deescalated. However, should it begin to increase in prevalence compared to other variants they will like escalate it.
does this help?
Thanks. So it's less transmissible than delta? I'd also guess that the data is still very limited (<1000cases).
That would be my guess. I took a look at the WHO's variant tracking site and it looks like epsilon may have been around longer than most other variants. If this is true then that would double suggest that it is not as highly transmissible as other variants and maybe even wild type. Do we have an epidemiologist on the caf?
2 weeks after easing restrictions cases are rising quickly in NL, who'd have thunk
What percentages of adults have had their jabs?
I'm looking for that figure. 16m jabs have been given, population 17m. 12-17 year old can get jab. Nearly all the new cases are people that have not been vaxxed or have had 1 jab only.
If that’s true the effectiveness of the vaccines is insane
If it's true, why do we have some people who expect another wave and lockdown in the UK given the success of the vaccine campaign?
73% 1 dose 44% both. So still plenty of room for it to spread.
Those sound like the over 18 vaccination percentages. When it comes to case rates unfortunately I think we need to look at population level numbers.
I'm curious who's not had it and why
Looks like the rise is in 20-30 year old, no surprise
I’m hoping this is a joke.
Because you don’t definitely have Covid until you test positive. To be afraid of a Swab and expect to discuss your ‘illness’ online is so childish. Get another test. You’ll probably need another ten in the next 2 years. Harden up.
Dunno if I’m the only one but I quite enjoy sticking the stick up my nose. There’s a weird euphoria too it. It’s also quite a challenge to not sneeze when doing it. Ive used up all twenty of my home kits purely to experience shoving the stick up my nose.
In the Sydney outbreak 3 people in their 80's and 90's have tested positive but so far are not symptomatic which is pleasing.
Based on the fairly terrifying case numbers in the UK in the past few weeks the deaths should be at 100+ per day by now going off the last peak - and are currently averaging about 15-20.
Hopefully this means the vaccines are doing a pretty damn good job.
Hopefully this means the vaccines are doing a pretty damn good job.
That’s probably as weird as not wanting to do it at all. It’s the throat part I can’t stand. I have a terrible gag reflex apparently.
This is too easy...
Anyway @SirAnderson It seems like you have it. So just wait 10 days from your first symptom started. Then if by the end of 10 days you don't have any fever nor new symptom nor symptom getting worse, then you should be out of it. Just isolate yourself till that end of 10 days.
This is scarily reminiscent of “something weird is happening in Kent” concerns from autumn last year
at this stage i think we are not anywhere near the end of this poxy virus.
Thanks @Isotope I have been isolating so far. It been about 8 days or so, my wife is positive and is over 12 days since see presented symptoms.
Have a question though, at what point is it no longer contagious? After 10 days?
If it’s like this during the summer, the winter is going to be another write off.
No idea how retraining works, will have to look into it.
Are you a smoker (ex or current)? My brother in law is one (me too) and it's the same with him, he can't smell the shittier stuff
We in our winter months here and its crazy. Level 4 lockdown and probably will only peak mid August.
The official guidelines, at least in US, is to isolate at least 10 days since first symptom started, or 10 days since testing date if asymptomatic. If you are sure that your wife was infected with the same virus type as you (getting from the same source), then you are free to be in contact with her (assuming she's out of her isolation already); since her body has that immune system (for at least 2-3 months or so).
If you'll be in contact with high risk people, then I suggest to get retested by the end of 10 days, or to isolate for 14 days (and meet those conditions I said on early post). If not, 10 days seems like the magic number for isolation.
Cool, thanks, pretty sure it came from the same source yeah. Appreciate the feedback.
This is scarily reminiscent of “something weird is happening in Kent” concerns from autumn last year
Yes, history repeats itself unfortunately
Prob a silly question but why don’t we see new variants in Ireland? We are close to the U.K. and yet the U.K. keeps spawning new ones
Yeah I threw it out there waiting for a childish reply from someone.