SARS CoV-2 coronavirus / Covid-19 (No tin foil hat silliness please)

I don't believe any of them have data for a single jab 3 months out do they?

https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)32661-1/fulltext

60.3% efficacy with a 12 week gap, considering the large percentage of the population will receive the AstraZeneca vaccine, and with supply hitting critical mass in 12 weeks, the decision by the JCVI to prioritise the first shot roll out to assist in the hospital pressures the right one. Which will have a greater impact than any lockdown that people want to talk about.

The Pfizer one is an unknown, however the JCVI wouldn’t have started conversations on single dose administration back in July, if they didn’t have a degree in confidence of its efficacy.
 

I will happily be corrected here, but that reads to me that AZ vaccine is shown to be effective AFTER a second dose is given at 12 weeks. It doesn't comment on what the protection level is like before the second dose is given, i.e at 11 weeks and 6 days.
 
2 weeks after the first jab or second jab? Wasnt the UK looking at delaying the 2nd jab because the first jab will do the job for now ?
In the leaflet she was given it says after the 2nd jab. It says 12 to 14 days after the 2nd jab in the guardian article that the Pigeon posted too. Doesn`t sound too good.
 
I will happily be corrected here, but that reads to me that AZ vaccine is shown to be effective AFTER a second dose is given at 12 weeks. It doesn't comment on what the protection level is like before the second dose is given, i.e at 11 weeks and 6 days.

Albeit a small data set:

https://www.bmj.com/content/372/bmj.n18

The trials of the Oxford-AstraZeneca vaccine did include different spacing between doses, finding that a longer gap (two to three months) led to a greater immune response, but the overall participant numbers were small
 
at least the daily cases are coming down, which will mean the death rate will also too. coupled with the vaccine rollout, today is hopefully the peak in terms of deaths. shocking number though.
 
Pretty much no one in Serbia wants to get a shot so I, 33 in May and with no chronic problems, am getting my first shot on Thursday.
 
Not great news coming out of Israel about delaying second dose of Pfizer vaccine.
Key caveat in that article:

...although the public health services head, Sharon Alroy-Preis, said that in most cases this was because the individuals had not built up sufficient antibodies after being inoculated before being exposed to the virus.

Could be a case of folks prematurely getting out and about, thinking they're protected so soon after receiving the jab.
 
I appreciate your contribution in this thread but you seem to be constantly bearing bad news. :nono:

Well there’s not a whole lot of good news out there!

Here’s some neutral news. ICNARC publish weekly summary of covid patients in ITU.

As of this week, the summary (page 76) indicates:
- A mean age of 60
- 65% male
- 30% non-white
- 10% with severe comorbidities
- 50% BMI >30
- 8% pregnant
 
Key caveat in that article:



Could be a case of folks prematurely getting out and about, thinking they're protected so soon after receiving the jab.

Definitely. Already hearing a lot of anecdotal reports of hospital staff coming down with covid a week or two after vaccination. Which isn’t surprising as the Pfizer study seemed to show protection only kicking in on day 10. Need to wait at least 3 weeks (with or without second dose) to get a good level of protection.
 
New strain in SA likely to be more resistant to vaccines :nervous: :nervous:


 
According to the WHO, its one and only mission is to "promote health, keep the world safe, and serve the vulnerable". Yet it still fails to achieve, and one of the most successful regions combating the pandemic (Taiwan) is banned from the WHO. What an irony. Trump might be wrong in many things but you can't really blame him for withdrawing from this corrupted organization.

I don't see that in it's constitution. From Wikipedia quoting their constitution "The WHO Constitution, which establishes the agency's governing structure and principles, states its main objective as "the attainment by all peoples of the highest possible level of health." The WHO have had huge success and I think you are misunderstanding its role and how it operates. It isn't set as a world health police but is just a specialist unit of the UN but it is mainly a managerial bureaucracy and will need some redesign if it is to become the pandemic response unit. It has had many great successes and the world would be far poorer (and fewer in number) without it. If you said it is too bureaucratic, sensitive to politics and slow moving in general I'd agree, but to lay the pandemic at its feet is drawing a very long bow. There was more than enough information out there for governments (who should be making the actual decisions) to act in time, as did a few countries, but to lay the blame for the incompetence of many government at the feet of the WHO isn't fair or reasonable.

Taiwan not being part of the WHO is because it isn't part of the UN which is tied up with relations with China. The WHO can't decide who is part of the UN and in any case what that has to do with the WHO's pandemic response isn't clear. And I do blame trump for cutting funding to the WHO because it was a purely political act. If you want them to change keep funding and negotiate KPI's. Don't cut them off at the knees mid pandemic. Like everything Trump did that was idiotic and hopefully Biden will reveres it ASAP.
 
New strain in SA likely to be more resistant to vaccines :nervous: :nervous:




The tweet oversells the actual paper. The strongest statement they make is

These data highlight the prospect of reinfection with antigenically distinct variants and may foreshadow reduced efficacy of current spike-based vaccines.

They say their data may mean people who had one variant of covid may be more prone to reinfection with this new variant and that this means it is possible some/all vaccines may be less effective.
 
I don't see that in it's constitution. From Wikipedia quoting their constitution "The WHO Constitution, which establishes the agency's governing structure and principles, states its main objective as "the attainment by all peoples of the highest possible level of health." The WHO have had huge success and I think you are misunderstanding its role and how it operates. It isn't set as a world health police but is just a specialist unit of the UN but it is mainly a managerial bureaucracy and will need some redesign if it is to become the pandemic response unit. It has had many great successes and the world would be far poorer (and fewer in number) without it. If you said it is too bureaucratic, sensitive to politics and slow moving in general I'd agree, but to lay the pandemic at its feet is drawing a very long bow. There was more than enough information out there for governments (who should be making the actual decisions) to act in time, as did a few countries, but to lay the blame for the incompetence of many government at the feet of the WHO isn't fair or reasonable.

Taiwan not being part of the WHO is because it isn't part of the UN which is tied up with relations with China. The WHO can't decide who is part of the UN and in any case what that has to do with the WHO's pandemic response isn't clear. And I do blame trump for cutting funding to the WHO because it was a purely political act. If you want them to change keep funding and negotiate KPI's. Don't cut them off at the knees mid pandemic. Like everything Trump did that was idiotic and hopefully Biden will reveres it ASAP.
That is the mission they claim and it is quoted in numerous papers. I agree they have had huge success in stopping the spread of various diseases, but certainly not in this pandemic. I do not expect them to become a pandemic response unit, quite the contrary if they had done their job there wouldn't have been a pandemic at all. They recommended against issuing a travelling ban to China in January, missing the best shot to contain the virus within Wuhan, or at least within China. By that time, there was little information and governments had no choice but to foolishly follow their advice. After this point, all efforts are just damage limitation. Yes some countries are handling better than others; but to me, the one who causes the damage shoulders a much more responsibility than those who fail to limit the damage.
 
A new study on the virus, looking at different forms of airborne spread. A reminder that it doesn't take someone coughing or even shouting to spread it.
https://www.theguardian.com/world/2...pread-covid-as-much-as-coughing-says-research

They also offer a calculator for looking at mitigation strategies (like face masks, improved ventilation etc). To be used with caution in terms of the absolute numbers/percentages it produces, because it assumes the covid carrier is someone exhaling a high viral load (the superspreader scenario) but it's handy for comparisons.
https://airborne.cam/
 
A 108-year-old lady in Milan was vaccinated yesterday - she's already had Covid and recovered! She's probably the oldest person in the world to date to be vaccinated.
 
A 108-year-old lady in Milan was vaccinated yesterday - she's already had Covid and recovered! She's probably the oldest person in the world to date to be vaccinated.

You'll probably find this useful. Running total of how many people have been vaccinated in Italy and how many of different vaccines have been delivered.

6k so far have had both doses. New administrations will be slowed a little so nobody misses the second dose.
 
I see Patel has come out and said they should've closed the borders early last year. Not really unexpected coming from her but about the first time I've seen a cabinet minister admit a mistake.
 
You'll probably find this useful. Running total of how many people have been vaccinated in Italy and how many of different vaccines have been delivered.

6k so far have had both doses. New administrations will be slowed a little so nobody misses the second dose.
Thanks! It's filtered down to our little village, as I mentioned the other day - all the care home staff and residents have been vaccinated. I was very pleased to see that the vaccine was getting to every small community.
 
It's nightmarish in Portugal. Terrible negligence of the government in relation to Christmas and New Year.. We're close to topping the charts in deaths per million. Or actually top according to some sources.
 
How come?

Some think that they will outright use them to insert chips into people while the vast majority think that they have not been tested enough and that at least 10-20 years need to pass in order to be really sure.

This has been discussed in this thread, @Sarni said that the situation in Poland is similar. Generally, there is a lot of vaccine resistance in the Eastern countries.
 
Some think that they will outright use them to insert chips into people while the vast majority think that they have not been tested enough and that at least 10-20 years need to pass in order to be really sure.

This has been discussed in this thread, @Sarni said that the situation in Poland is similar. Generally, there is a lot of vaccine resistance in the Eastern countries.

Interesting. I guess you always think of the US and the UK when it comes to misinformation but not really to much about European countries, especially Eastern Europe. I find it baffling that enough people think there will be a chip in it for the line to be skipped all the way to 30 year olds. Do they not realise they already literally carry a chip with them everywhere they go? Let alone the hundreds of other reasons why that is nonsense.
 
Interesting. I guess you always think of the US and the UK when it comes to misinformation but not really to much about European countries, especially Eastern Europe. I find it baffling that enough people think there will be a chip in it for the line to be skipped all the way to 30 year olds. Do they not realise they already literally carry a chip with them everywhere they go? Let alone the hundreds of other reasons why that is nonsense.

I am originally from Moldova and have several relatives and old friends on facebook. The amount of misinformation and fake news that is passed as 100% truth is mind boggling.
 
Interesting. I guess you always think of the US and the UK when it comes to misinformation but not really to much about European countries, especially Eastern Europe. I find it baffling that enough people think there will be a chip in it for the line to be skipped all the way to 30 year olds. Do they not realise they already literally carry a chip with them everywhere they go? Let alone the hundreds of other reasons why that is nonsense.

The US and UK are actually less vaccine sceptical than nearly every European nation.

https://www.euronews.com/2020/12/09...-to-be-most-hesitant-about-a-covid-19-vaccine
 
It's nightmarish in Portugal. Terrible negligence of the government in relation to Christmas and New Year.. We're close to topping the charts in deaths per million. Or actually top according to some sources.

What happened in the Autumn?
Pdnlfiv.png
 
Not great news coming out of Israel about delaying second dose of Pfizer vaccine.

Its pretty insane the amount of wasted vaccine. 1 vial of the Pfizer BNT162b2 RNA has 0.45 mL in it, we dilute it with 1.8 mL NaCl which is 2.25 mL together and 0.3 mL is given so if drawn up carefully thats theoretically 7.5 doses. After careful practice I've easily been getting 7 doses.

We are allowed to give the 6th dose with our "professional judgment" which we have done but I'm finding a lot of wastage still.

I think there's plenty of vaccine to go around to fulfil second dose commitments on time if we had some help from government to scale up primary care operations with some support. Consenting doesn't require you to be a brain surgeon and neither does giving the damn thing. I had a senior clinician on site who made the decision and was always available for the grey areas where contraindication to vaccination was possible but tricky to gauge (e.g. anaphylactoid sounding reaction but didn't need adrenaline). The red tape and paperwork is a bit insane and much, a lot of things to sign and do around it but its really not that difficult to find people who will be able to do this in a safe, competent way

Could easily scale up what primary care physicians are doing to 24 hours if supply can be sorted and a bit of support, high percentage of population turning up and making the effort to get the jab. I think demand will be there.

A few GPs kicked off majorly and have gone rogue against government guidelines to deliver the second jab but thats rare. There are a few legal challenges pending with regards to the retroactive changing of consent (for those who consented to vaccine predicted on receiving the second 21 days after as per manufacturer)

The data from Israel is worth considering for sure in terms of a shift in policy.
 
Curfew in The Netherlands from 8:30pm - 4:30am.

The conspiracy nuts are saying we are back in 1940 and we will be forced to all wear the same clothes and wear gps bracelets soon.

Fecking snowflakes.