SARS CoV-2 coronavirus / Covid-19 (No tin foil hat silliness please)


I wouldn't take that completely literally - there are degrees of "made" and there's a difference between made and available. Made could mean it's been processed and it's in its in the vat, or it's in its barrels, or it's in its vials ready to test and ship.

Available means it's in vials, with the correct paperwork, labelling and it's been batch tested. If the story I read this morning is accurate, then the half million on Monday refers to doses in vials ready to use and available to the testing locations.

In terms of bulk product there are supposed to be 5m doses in the UK. Not the 30m before the end of the year that one of the government ministers suggested a couple of weeks ago, but not a trivial quantity either.
 
After I posted that I found a report that I could actually understand. It gives a secondary attack rate of 15% vs 9.9%. Which is about a 50% increase in transmissibility. Feck.

So as I understand it the attack rate still allows for variation in the strains to be influenced by the behaviour of the people with those strains and the context they’re contracted in, and we lack proper lab testing to put a specific number on how much more infectious it is and explain some of the mechanisms behind it. They’re not RCTs with all that comes with that, and matching based on demographics can only take you so far. But yeah they seem pretty certain it’s something of a game changer, even if we lack some specifics.

Not sure what can be done about that. Might be time to become a hermit to help us stumble across the line.

The most surprising part of the u-turn is that they still haven’t fully done it to include secondary schools yet.i assume this will come in a few more days.

Yeah if they close primary schools and not secondary schools then I don’t think their position is defensible any more. There is an abundance of evidence that says primary schools pose less danger than secondary schools in almost every way, going back months. If you think primary schools need to be closed, you have to think secondary schools need to be closed. The only difference could even partially explain things is the parent interaction. Maybe they’re finding parents spreading it a lot among themselves when picking up and dropping off kids at a time when transmission is so high. Because everything that happens outside of that is worse for older kids.


feckin hell. Well, I guess being married to a Covid nurse and having to teach & coach through this, I should expect to have a few scares of Covid and all... but it still does get nerve wracking.

As of about Noon today, I've lost all sense of smell. I've also got some pain in my sinuses and a general tired feeling all over.

But out of nowhere, I can't smell a single damn thing.

That sucks man. Hope it works itself out. Take care of yourself in the meantime!
 
feckin hell. Well, I guess being married to a Covid nurse and having to teach & coach through this, I should expect to have a few scares of Covid and all... but it still does get nerve wracking.

As of about Noon today, I've lost all sense of smell. I've also got some pain in my sinuses and a general tired feeling all over.

But out of nowhere, I can't smell a single damn thing.

That’s shit news. Assume you have it and behave accordingly. And get well soon!
 
Shit - I hope you are ok.
That sucks man. Hope it works itself out. Take care of yourself in the meantime!
That’s shit news. Assume you have it and behave accordingly. And get well soon!
I appreciate the well-wishes folks.

My wife’s work is getting me in tomorrow to get me tested, so I should know something by sometime Sunday/Monday.

I’m really the most concerned about her. Yesterday was our anniversary, and I felt perfectly normal then. Maybe the 1st dose of the vaccine will help her a bit if I do have it.
 
feckin hell. Well, I guess being married to a Covid nurse and having to teach & coach through this, I should expect to have a few scares of Covid and all... but it still does get nerve wracking.

As of about Noon today, I've lost all sense of smell. I've also got some pain in my sinuses and a general tired feeling all over.

But out of nowhere, I can't smell a single damn thing.
Ahh sorry to hear that, hope you recover quickly and fully soon. How do you reckon you caught it?
 
Ahh sorry to hear that, hope you recover quickly and fully soon. How do you reckon you caught it?
Well, assuming I do have it...

If not from my wife and her job, then likely from my job.

School has been out, but our state’s wrestling season runs through Winter Break, so I’ve been doing my coaching job and coaching the school’s wrestling team this whole time we’ve been out of school for break.
 
Are we getting some of that 50m?

If not, why do we have so few in comparison?
India is the king of vaccines in the world. Once they get up and running its truly impressive. They have they ability to manufacture so much more than anyone else.
 
India is the king of vaccines in the world. Once they get up and running its truly impressive. They have they ability to manufacture so much more than anyone else.
Ref cv19 vaccines I thought usa had most capacity... then India then China

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Allison Pearson, you’d think she’d have had enough of showing herself to be an enormous tool...

 
She seems the type of idiot who says all these nonsensical things but will also jump the queue to get a vacccine. Kinda like Murdoch.
 
Ref cv19 vaccines I thought usa had most capacity... then India then China

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They do but that will be various vaccines by different manufacturers and they won't necessarily be running at full capability. India will pick the cheapest one that works and just go for it full steam.
 
Ref cv19 vaccines I thought usa had most capacity... then India then China

55737572_7.png
I'm not sure how they calculated the UK number there. I suspect there's some double counting (vaccine manufacture + finish/fill being quoted separately because they're by different companies perhaps?) and some 2021 optimism about new capacity in places like VMIC/Harwell.

Covid has massively accelerated some of the timelines. VMIC wasn't expected to ramp up to production capacity until 2022 (it got funding approval in 2019). It should get there in 21 now. Similarly new capacity and upgraded facilities are happening on other sites, liked Oxford and Livingstone - but the key word is happening, not happened.

At present there's no mRNA bulk capacity in the UK. Similar "you can't make it here" provisos apply to some other vaccine types as well. Plus, as usual, you need some specialised reagents and chemical components that are often made in a single plant in another country - or a single regional plant.

For a vaccine like Novavax, the adjuvant for the European sites is being made in Sweden. The main vaccine production site is in Czechoslovakia. Finish and fill in multiple countries including Spain and I believe (if we have capacity by then) the UK. A lot of vaccines have similar looking supply chains. I would guess India (and the USA of course) have all the factories for all the stages.

You can get a hint of some of the manufacturing upgrades underway at:
https://www.google.com/url?sa=t&sou...FjABegQIAhAB&usg=AOvVaw20dz8O5pk49Z6hslnGKMYU
 
Made a U-Turn on London schools, closing all of them for 2 weeks it seems.

Clearly based on Science fecking clowns.
 

New variant over doubling it's proportion weekly in Denmark also. So will become dominant in 4-6 weeks. Would assume from this that France and Ireland have already much more of the variant than they think.

Europe will be fecked in March and April before weather and vaccines help.

Tweet is poorly worded. Means they have sequenced 11% of all the positive cases since November.
 

New variant over doubling it's proportion weekly in Denmark also. So will become dominant in 4-6 weeks. Would assume from this that France and Ireland have already much more of the variant than they think.

Europe will be fecked in March and April before weather and vaccines help.

Tweet is poorly worded. Means they have sequenced 11% of all the positive cases since November.


I’ve reached the point where I’m desperately hoping that Ireland has been overrun with this new variant for weeks (which seems to be likely) because if we’re getting the current explosion of cases before the new variant dominates then we’re absolutely screwed.
 
I’ve reached the point where I’m desperately hoping that Ireland has been overrun with this new variant for weeks (which seems to be likely) because if we’re getting the current explosion of cases before the new variant dominates then we’re absolutely screwed.
Irish officials just commented on Guardian that they believe 5-17% of cases are now new variant. Sounds about right. So will be dominant in 2-4 weeks. Unfortunately it will be only getting worse for you :( And there is back-log of 9.000 cases in Ireland and you will report over 3.000 today, according to Guardian.
 
Irish officials just commented on Guardian that they believe 5-17% of cases are now new variant. Sounds about right. So will be dominant in 2-4 weeks. Unfortunately it will be only getting worse for you :( And there is back-log of 9.000 cases in Ireland and you will report over 3.000 today, according to Guardian.

We’ve officially moved out of containment so have stopped testing close contacts. The case numbers are going to be a massive underestimation from now on. It’s the hospitalisation/ITU numbers I’ll be following closely and they’re increasing exponentially. It’s horrifying how fast this got away from us.
 
China has an incredibly compliant population ruled by fear, but they've cultivated this over years - it wouldn’t work in the UK or many countries for that matter.
I’d say fear is an exaggeration. They are compliant so long as they see the economic benefits. They are getting richer for themselves, their lifestyle is dramatically improving and many couldn’t care less about what happens at the top.
 
57725k cases in the UK and 445 deaths.

Germany vaccinated 130k as of 30th Dec, France just 138 people. Mainland Europe has a massive heads up to trace and vaccinate for around Mar/Apr when and if the new strain takes hold but it will be a battle of production and logistics.
 
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We’ve officially moved out of containment so have stopped testing close contacts. The case numbers are going to be a massive underestimation from now on. It’s the hospitalisation/ITU numbers I’ll be following closely and they’re increasing exponentially. It’s horrifying how fast this got away from us.
Yeah, it is more reliable but 2 weeks behind. Could look at combination of positivity rate and cases. I think you will have to be at level 4/5 until April. Just sad :(
 
UK records another 57,725 coronavirus cases in 24 hours - up from 53,285 yesterday

There have also been another 445 COVID-19 deaths within 28 days of a positive test, according to the latest government data.

This is down from 613 deaths recorded yesterday.
 
UK records another 57,725 coronavirus cases in 24 hours - up from 53,285 yesterday

There have also been another 445 COVID-19 deaths within 28 days of a positive test, according to the latest government data.

This is down from 613 deaths recorded yesterday.
That's with today being a Saturday and yesterday being a Bank Holiday. I think we'll see record numbers on Tuesday, unfortunately. It feels like a perfect storm brewing.
 
China has an incredibly compliant population ruled by fear, but they've cultivated this over years - it wouldn’t work in the UK or many countries for that matter.

It works least in the US (which would explain the high case numbers here) because people have been conditioned to be suspicious of government and concepts like freedom and liberty tend to creep into public policy - mainly by the right of course.
 
2500 people participated to a rave party in Brittany. :eek:
 
Yeah, it is more reliable but 2 weeks behind. Could look at combination of positivity rate and cases. I think you will have to be at level 4/5 until April. Just sad :(

Our positivity rate is horrendous. Been <2% for most of the year but 17.6% today. Apparently >50% in some centres. We’re in deep deep shit by every metric. Can’t fecking believe the vaccine procurement/roll-out is shambolic on top of all this. Think this might actually be the most depressed I’ve felt about the pandemic. Just when we were supposed to be seeing light at the end of the tunnel too :(
 
It works least in the US (which would explain the high case numbers here) because people have been conditioned to be suspicious of government and concepts like freedom and liberty tend to creep into public policy - mainly by the right of course.
Creep in? Isn’t your whole constitution built on those inaliable rights?
 
Creep in? Isn’t your whole constitution built on those inaliable rights?

There are limits to everything. We have freedom of speech, and yet we can't yell fire in a crowded theater. The same would logically apply to public health emergencies. You can walk around without masks indoors when there's no pandemic, but you can't do so when there is and your country is losing a 9/11 worth of people a day.