horsechoker
The Caf's Ezza.
Not his biggest fan, not even closeNigel Farage to relaunch Brexit Party as anti-lockdown Reform UK
https://www.cityam.com/nigel-farage-to-relaunch-brexit-party-as-anti-lockdown-reform-uk/
Not his biggest fan, not even closeNigel Farage to relaunch Brexit Party as anti-lockdown Reform UK
https://www.cityam.com/nigel-farage-to-relaunch-brexit-party-as-anti-lockdown-reform-uk/
At least lockdowns are at least technically feasible in the modern era. Imagine trying this before we had remote working, home deliveries and free porn.
Yep. If this hits us in 1998, I think we carry on and they basically just tell us 'wear a mask, and good luck'.I know, right? The other crazy thing to think about if this hit us 10-20 years ago is vaccines. There’s been a massive leap forward in the technology of vaccine development in the last 5-10 years. If this pandemic hit us before that we’d be looking at a minimum of several years to get a vaccine to market and whole classes of vaccine that had not yet been invented (e.g. the Oxford vaccine).
Yep. If this hits us in 1998, I think we carry on and they basically just tell us 'wear a mask, and good luck'.
I wouldn't even go that far. I think 2010 we'd do that. I remember my firm just had a very primitive and slow remote access setup back in 2012, that very few people even had access to.Yep. If this hits us in 1998, I think we carry on and they basically just tell us 'wear a mask, and good luck'.
As part of UK-CIC, researchers from the University of Birmingham, Public Health England, Manchester University NHS Foundation Trust (MFT) and NIHR Manchester Clinical Research Facility collected serum and blood samples from a cohort of more than 2,000 clinical and non-clinical healthcare workers including 100 individuals who tested sero-positive for SARS-CoV-2 in March/April 2020 (average age 41 (range 22–65); 23 men, 77 women). All 100 individuals experienced either mild/moderate symptoms or were asymptomatic (56 versus 44 people) and none were hospitalised for COVID-19. Serum samples were collected monthly to measure antibody levels, and blood samples were taken after six months to assess the cellular (T cell) response. A range of analyses were carried out to assess different aspects of the T cell response including the magnitude of response and the response to different proteins from SARS-CoV-2. Carrying out these cellular analyses is much more complex than antibody studies – but this study of 100 individuals is one of the largest in the world to date in this field.
T cell responses were present in all individuals at six months after SARS-CoV-2 infection. The cellular immune response was directed against a range of proteins from the virus, including the Spike protein that is being used in most vaccine studies. However, comparable immunity was present against additional proteins, such as nucleoprotein, which suggests that these may be of value for incorporation in future vaccine protocols. This indicates that a robust cellular memory against the virus persists for at least six months.
This thread’s been very light on good news recently but this preprint is fairly encouraging.
How are hospitals in the UK coping ? Any doctors or nurses as some reports say we are in trouble where as others say it is exaggerated . Is Belgium really as bad as being reported?
Anyone know why it is so bad in Belgium?Yes, it is atrocious. I live in the Netherlands but have friends in Belgium who I regularly meet(online for drinks and card games) and they tell me the situation is absolutely dire.
If its anything like NL, people dont care, no policing. Simple as thatAnyone know why it is so bad in Belgium?
Yeah I've seen those discussion for those venues. My take is that take away pints, just promotes drinking in the street and thus increasing contact. Struggle to see that changing. Home delivery could be an option, and that is a viable method maybe, my local bar delivers to home and works really well (cocktails, beer, casks). Some of these businesses need to become a little more dynamic to keep their business resilient.
Gym's is an interesting one, I've not seen any scientific study on the impact of people in there and transmission rates. The cynic in me thinks that these businesses wouldn't have led with a mental health argument, but it's the strongest argument they can use to remain open. If it was really about mental health, then they wouldn't mind giving their services for free.
Great question! Never really understood that myself. Where do seasonal viruses hide during summer? I’m sure google could throw up some theories. I’m too lazy to check though.
How is that good news? Only 6 months? So we would need 2 vacines a year.Some good news about t-cell longevity https://www.theguardian.com/world/2...er-first-infection?CMP=Share_AndroidApp_Other
How is that good news? Only 6 months? So we would need 2 vacines a year.
I hope so.They have only tracked them for 6 months so far so they may well last much longer. Every person was found to have t-cells even if they had low or even no symptoms. People with worse symptoms had even more and hopefully the longevity as a result of a vaccine will be as good or better than these cases. So I'd say very good news as far as it goes.
Herd immunity may well require in excess of 50 million people to be infected or vaccinated.
On the plus side, I think if it hit in 1998 then it would have led to a much better community effort and more sustained action by people to help decrease transmission.
Plus we wouldn't have all felt that nauseating ache in the back of our brains that we're missing out on living life to the max.
I always thought around 60% and you wouldn't be far off. That would be just over 35m in England.
I listened to a podcast where an epidemiologist did a rough estimate on what it would it take to reach herd immunity without a vaccine. They figured at least 5 or 6 waves.
I live on my own mate.
I listened to a podcast where an epidemiologist did a rough estimate on what it would it take to reach herd immunity without a vaccine. They figured at least 5 or 6 waves.
When I'm listening the radio and hearing people argue xyz should remain open due to mental health, I can't help but think a lot of people want us to believe we are less resilient than we are, for their own purposes (to stay open)
Is the mental health argument being used to try and save businesses that are on poor financial footing?
They have only tracked them for 6 months so far so they may well last much longer. Every person was found to have t-cells even if they had low or even no symptoms. People with worse symptoms had even more and hopefully the longevity as a result of a vaccine will be as good or better than these cases. So I'd say very good news as far as it goes.
Edit: Pogue posted about this yesterday as well. Or rather
These results provide reassurance that, although the titre of antibody to SARS-CoV-2 can fall below detectable levels within a few months of infection, a degree of immunity to the virus may be maintained. However, the critical question remains: do these persistent T cells provide efficient protection against re-infection?
It’s not just Europe and North America though. South America’s been absolutely hammered. India’s having a terrible time. Case numbers are peaking in Iran and Israel’s had a second full lockdown already.
We also somehow have close neighbours having very different experiences to other countries in the same region. Pakistan doesn’t seem to be having a second wave, or Saudi Arabia. And the continent of Africa is a patchwork of very different caseload graphs.
It’s very hard to work out why different countries are/aren’t having a second wave but there’s more to it than just Europe/North America making terrible decisions.
It’s probably easier to look at the very small number of countries that seem to be doing well. The common themes seem to be geographic isolation and low population density and/or prior experience of dealing with a novel viral epidemic.
While both of these statements are true I'm not sure they tell the story you're alluding to. Business travel has dropped off a cliff everywhere and will recover much more slowly than leisure travel, so comparing business travel in Asia to leisure travel in Europe will only mislead.
From a quick glance at this data, people in Asia are travelling quite a lot on planes. There were 28m seats available on the w/c 19th October in APAC compared to 43m a year earlier, while there 11m seats available in Europe compared to 29m a year earlier. In other words the drop-off in European flights has been much more severe, even now. Or if you look at this data, Asian travel has been steadily increasing to now be the top travellers. That's domestic and international overall, and it's just the case that a larger proportion of European flights have always been international, so it's difficult to do a side by side comparison regionally.
If you take Japan as an example, 140k seats were available for international flights vs 1.2m a year earlier, whereas for the UK 930k seats were available vs 3m a year earlier. So Japan's international demand fell to 12% of normal levels while the UK's fell to 32%. And generally speaking European borders have been open much longer and to a much wider range of countries than Asia's. But then if the notion is that movement of people across medium-long distances through airports and planes is a major source of transmission, then domestic flights are still a risk factor and Asia are doing a lot more of that at the moment. And if you assume that most people are moving from areas of higher community transmission to lower community transmission, or maintaining a similar level, then the end destination doesn't matter all that much.
What would make a difference is the kinds of holidays people take and the propensity to do things in large groups, and from the data I've seen whether it was Asian travel (which has a tradition of large group cultural tours) or European travel (which obviously leans more to large group partying), there was much more travelling among small groups than usual. At the end of the day, most transmission that we're able to track comes from within our own borders. It's only the countries that have managed to keep it under control exceptionally well within their own borders (e.g. Germany) that can point to a significant proportion being imported in.
Thanks for this data, very interesting.
Doesn't the second set show that flights in the AP region are down by the same amount as Europe for domestic travel but more for international travel?
Regardless, I was being a little flippant. It isn't so much that I was saying that flights and travel are the major driver of new infections, more the impression that it gave off generally that we'd beaten the virus and could essentially go back to something like life as normal across the continent.
The article I posted in the comment above says a bit more eloquently what I was trying to say generally I think.
Nah. One of my neighbours is severely autistic and goes and sits in the same cafe every single day at the same time. Closing that cafe is destroying her mental health, but that doesn't mean we shouldn't close cafes.I think there should be a strong consideration for gyms, some gyms at least, to stay open as long as they pass a Covid compliance test and can prove they have sufficient process to ensure distancing and hygiene measures are adequate.
Gyms and working out are in my view essential for some people’s mental health, mine included. I’m fortunate that I have a gym at home and have been able to carry on working out but I’d be struggling if that wasn’t the case.
Nah. One of my neighbours is severely autistic and goes and sits in the same cafe every single day at the same time. Closing that cafe is destroying her mental health, but that doesn't mean we shouldn't close cafes.
If gyms are closed, go for a run.
I just don't really see what can be done in a gym that can't be mirrored in some way at home or outside? Sure, you might not have access to heavy weights or specific machines at home or in the park, but you can quite easily do a decent workout that gets the heart going and the muscles working. Is it ideal? No. We're all having to give up cherished routines and adapt to this shitty situation. Someone might not be able to obtain their peak physique or rack up the gains or play their favourite sport at home... but that's hardly the priority in a pandemic. Keeping fit is perfectly possible.Cafe's not quite the same in my opinion, hard as I'm sure it is on your neighbour and the thought of your neighbour is heartbreaking. Gyms are of great benefit, both physical and mental, to us as individuals. They're not just a pointless tentacle of capitalism and in my view are bordering on necessary as some people use them for pure health reasons. I've seen how some (some, though not all) gyms have dealt with the current situation and don't feel they are necessarily a Covid breeding ground.
Even so, I understand it can't be a totally selective endeavour, and I am very pro-lockdown but I wouldn't be concerned, or surprised if some gyms we allowed some slack if they could prove compliance. Going for a run isn't possible for some people.
Apologies, completely forgot about replying to these posts.
Its true that those other countries are having a terrible time of it too, though perhaps only Iran and Israel of those have had true second waves, as opposed to continuations of first waves. The likes of Mexico and Argentina have never properly gotten case numbers down in the way that we managed across much of Europe and are just stuck in an increasingly severe 1st wave it seems.
I think the bolded part is certainly very important, though it is still pretty galling that we sacrificed so much in the first set of lockdowns and seemingly have been unable to use that and subsequent lull to build systems to deal with it, on top of what should already be very efficient PH infrastructures.
Saw this interesting....and slightly inflammatory! article yesterday in the Irish times that describes what I was trying to say in a more articulate manner. The first comment is just so classic as well.
https://www.irishtimes.com/opinion/...-made-a-mess-of-handling-the-crisis-1.4395473
The West has failed – US and Europe have made a mess of handling the crisis
Western leaders have been insular slow learners at every stage of the Covid pandemic
Someone might not be able to obtain their peak physique or rack up the gains at home... but that's hardly the priority in a pandemic. Keeping fit is perfectly possible.
It's a fair point. I'm not denying there are health consequences to closing gyms and other sports facilities. Hopefully they're not shut too long.And I agree but there are lots of old people using gyms to retain health and some muscular strength under supervision of qualified professionals. Lots of people in some kind of rehab. I was / still am a well qualified PT with a medical referral qualification and there will be lots of people affected physically by the closure of gyms.
But, I'm not contesting the decision, just pointing out that gyms could be considered necessary business.
It's a fair point. I'm not denying there are health consequences to closing gyms and other sports facilities. Hopefully they're not shut too long.