Actually given what I am told is happening in and around Angela Rayners constituency, she is the one who might lose her seat.
Angela Rayner had a majority of around 4500 last time. Around 20% of voters are Muslim and with George Galloway's constituency being just up the road and he has fired up a number of Muslim /Labour voters about Gaza, so some danger there. Plus (so, I'm am told by friends who live in the constituency *) Reform is also taking potential voters from Labour, as well as Tories.
The Tories have repeatedly targeted Rayner and being as they are going down anyway, it's possible some 'dirty tricks' may be in play and they may well encourage their local people vote Reform to get Rayner in a 'pincer movement'.
So Labour could have a vacancy for a parliamentary deputy leader.
(* I lived in the area for many years and its always been a Labour safe seat, indeed the joke use to be you could pin a red rosette on a dog and it would get elected)