Just a random thought, but if a bad reaction to a vaccination is due to the way a particular individual's immune reaction kicks in, does that mean the same person might also be one of those that would have suffered the most if they contracted the actual virus?
Maybe those that have had the worst experience of vaccination are those that needed it the most anyway?
Yep, fairly common reaction to the first dose of the AZ/Oxford vaccine.
It floored me when I had mine - had to dose up on paracetamol. But passed after 36 hours or so. Roll on the second dose!
Not with the AZ but I had the Pfizer jab and felt like that. It’s just the body immune system kicking in. My brother was the same for a day. But next day was absolutely fine. I had mine while I was at work as well on a night shift. Had my second about 3 weeks ago and had no effects at all.
Yeah good stuff. I'm completely side effect free today.
Got my 2nd dose booked in for the middle of May.
Could be. The more likely scenario is they had covid asymptomatically before and the vaccine is amplifying the symptoms that were hardly noticed the first time.
This is anecdotal of course.
From a jab?Bugger, just hopped into bed for the night and winding down, getting hit with chills and more muscle soreness as i relax
How are you getting on JMack? If I remember rightly you were struggling with the lockdown this time last year. Being an introvert with loads of Uni work I was more than happy to be locked in at the time so probably wasn’t particularly understanding of how difficult it was for people who need social interaction to function. I’m still a firm believer of how necessary its all been but as it’s went on and on I’ve understood more how draining it can be for others and why you might have been so against it at the time.
Yeah, got AZ at 11am, initial symptoms were sore arm and headache that was controlled by paracetamol. Rest of work day was fine. However got ready for bed and started to unwind.......BAM chills, fever, whole body soreness.From a jab?
Oh I see, well hopefully doesn’t last too long. Get well soonYeah, got AZ at 11am, initial symptoms were sore arm and headache that was controlled by paracetamol. Rest of work day was fine. However got ready for bed and started to unwind.......BAM chills, fever, whole body soreness.
I was out for 36 hours after my first dose. Apparently the side effects are meant to be worse after the second dose. Due for mine in April. I think I might just preemptively tell the hospital I won't be in for two days I'd be lying if I said I'm not a bit nervous about how bad I'll feel, even if it's only temporarily. Haven't felt that sick in years.
Really makes you think about just how awful getting actual Covid might feel.
Although what you felt was likely more a side effect of the immune response (or the adjuvant which often causes inflammation more generally to speed up the immune response) than it feeling like having covid.
Why do some people have mild reactions but some have more severe ones?Although what you felt was likely more a side effect of the immune response (or the adjuvant which often causes inflammation more generally to speed up the immune response) than it feeling like having covid.
Hope she gets better soon. Scary times for herA friend of mine had a heart attack 6 weeks ago , 64 years old , so missed out on her jab . She had a stent put in and has been home now for 4 weeks and got called last week for her jab . She had a bad reaction and had to go back to hospital in Ysbyty Gwynedd , Bangor where they currently have an outbreak where about 50 people have caught covid. She has been released this morning so hopefully she will be ok now, scary stuff though.
It is . I saw her husband when I was walking passed the house this morning and he said she seems ok but it is quite scary . She`s a tough old boiler so hopefully she will be ok.Hope she gets better soon. Scary times for her
Why do some people have mild reactions but some have more severe ones?
Why do some people have mild reactions but some have more severe ones?
We don't really know beyond conjecture I believe. Despite it probably being a multifactorial thing, there is an interesting field though looking into it at a cellular/genetic level called "adversomics" which has hypothesised that genes that code for inflammatory proteins called interleukins (and specific pro-inflammatory or fever-promoting subtypes) may be implicated.
We found that a single dose of mRNA vaccine elicited rapid immune responses in seropositive participants, with post vaccination antibody titers that were similar to or exceeded titers found in seronegative participants who received two vaccinations. Whether a single dose of mRNA vaccine provides effective protection in seropositive persons requires investigation.
I could fecking cryAZ vaccine roll-out on hold in Ireland after more reports of blood clots, this time from Norway.
I could fecking cry
It’s worrying though that it’s a trend with several countries now.If they decide these cases are unrelated it will only be a pause for a few days. They’re erring on the side of caution while this is investigated. Could be full steam ahead by middle of this week.
It’s a PR nightmare though. Music to the ears of antivaxxers.
Apparently theres higher percentage of people in the general population who gotten blood clots than there are among people who’ve got the jab. Hopefully the blood clots are totally unrelated to the vaccine.AZ vaccine roll-out on hold in Ireland after more reports of blood clots, this time from Norway.
It’s worrying though that it’s a trend with several countries now.
but then I see U.K. has done millions without these reports and I’m thinking crack on ffs
If they decide these cases are unrelated it will only be a pause for a few days. They’re erring on the side of caution while this is investigated. Could be full steam ahead by middle of this week.
It’s a PR nightmare though. Music to the ears of antivaxxers.
Are the new cases amongst those that have been vaccinated or those that have not yet been vaccinated?The selection of an effective vaccine is really crucial. Look at Chile, their case number keeps rising after they launch their vaccination campaign.
Isn't covid itself linked to higher incidences of blood clots?
If they decide these cases are unrelated it will only be a pause for a few days. They’re erring on the side of caution while this is investigated. Could be full steam ahead by middle of this week.
It’s a PR nightmare though. Music to the ears of antivaxxers.
I don't have detailed information. But in countries with a massive vaccination campaign (e.g. US, UK, Israel), the total case number as a whole should fall steadily irrelevant if an individual is vaccinated or not.Are the new cases amongst those that have been vaccinated or those that have not yet been vaccinated?
Arithmetic would say not. It would depend on the proportion of the population vaccinated and the rate of infection amongst the unvaccinated. You need figures to back up your theory.I don't have detailed information. But in countries with a massive vaccination campaign (e.g. US, UK, Israel), the total case number as a whole should fall steadily irrelevant if an individual is vaccinated or not.
US:Arithmetic would say not. It would depend on the proportion of the population vaccinated and the rate of infection amongst the unvaccinated. You need figures to back up your theory.
The NIAC's statements are a bit strange though, I get precautionary principle. But they literally said on Friday they wouldn't recommend deferment, then another statement today they would recommend it but will meet again today and possibly say something different.
I suppose I may not be cognisant of any precedents or frameworks and how certain health agencies might be compelled or bound to act certain ways regarding vaccine provision should there be any concerns, however small to look into side effects.
There were low platelet reports for the Pfizer earlier this year. As usual trying to see the wood for the trees comes down to looking at the big numbers of people vaccinated and comparing the incident reports to whatever is the normal annual rate in similar groups. On analysis those just looked like coincidence, but of course no one can rule out the idea that the vaccine (and the immune response to it) could be the trigger, just as covid itself triggers other problems.It is. Well, coagulopathies in general.
It’s a really complicated picture. The Austrian issue was a pulmonary embolus. Which is a clot. The issue in Norway seems to be excessive bleeding, due to low platelets.
Covid messes with your clotting pathways and can causes clots and bleeds. But I don’t think it’s associated with low platelets.