The vaccines | vaxxed boosted unvaxxed? New poll
- Thread starter Badunk
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France gave priority to the OAP /care homes and medical /strategic workers and people at high risk and are now working through the age groups.
Currently 60+ for Pfizer & Moderna , both of which have been available since vaccination started and now at vaccination centres, which in our case is at the medical centre in a nearby small town. (our age group)
The 55+ group can book AZ & JJ at their GP or Pharmacy. There is hesitancy concerning the last two but all the appointments have been taken.
I made our appointments the day they became available by checking on line every hour throughout the day but they quickly went and now I believe there's a several weeks waiting list.
The vaccination centre has plenty of volunteer staff , we're in a low populated area, it was all very well done.
Touch wood, I have had no effects in the first 24 hours but my wife's arm aches a bit
I took my second jab this morning. Sinovac. The first time I felt fine, minor throbbing pain on injection site aside. This time around I felt a bit drowsy a few hours after, which went away after a short nap, and my upper left arm is feeling very sore with movement.
I guess it's just the vaccine doing its thing.
I guess it's just the vaccine doing its thing.
I don’t even...
I cant say i am even remotely surprised Russia is acting the fool here. Some people just want to watch the world burn.
Having defended Sputnik from the "can you really trust what they say" thing, following their release of Phase 3 interim data, they aren't half making me backtrack.
I hope this continues to see a big uptake of the vaccine as I was a little concerned at the first signs of some slots not being filled from a article I saw Monday. 227,000 vaccinations slots were still available Monday apparently.
https://www.letelegramme.fr/bretagn...s-preneur-en-bretagne-27-04-2021-12741485.php
When I was at the vaccination centre yesterday there were people phoning up who were clearly unsure of how to book their appointments by listening to the replies of the staff, especially the older patients.
As the age groups get younger I would expect younger people would be more internet literate and understand more easily how to reserve their vaccines.
It's a good article on the broad principles. Certainly, when it comes to pandemic preparedness, the ability to manufacture the new generation of vaccines globally is crucial. I think it underestimates the timeline for that though.
The role of individual engineers/scientists shouldn't be underestimated when it comes to production knowledge transfer. The Pfizer plant have now been through the production loop lots of times, maybe even dozens and will have undergone multiple tuning steps to get to safe running capacity. The actual number of key people involved in that design tuning/process tweaking will have been tiny though.
Some of them may now be able to go and create a similar line elsewhere. But it would still take months to modify an existing factory - and shortages on raw materials, components, and freezer technology might still interfere. It's arguable a better use of their time would be to create a kit that could be cloned for future use.
On AZ and J&J. Well, J&J had already said their IP is available to anyone who can use it - but they've had trouble getting their own facilities up to full production. As far as I know only one of the European plants has reached production volume so far - I'd suggest they don't yet know enough to know-how share.
The same's true for Novavax (though that's a different technology again). All the indications there are that they're still learning how to make it.
SII are the biggest producer of the Oxford/AZ vaccine. It's already being produced on multiple sites globally, and it probably could have gone wider if it hadn't had quite so many issues (and such terrible PR). I'm happy to argue that AZ remains a good option for most of the world, but its rejection by South Africa (where its performance against the variant looked weak in trials) will make it a tough sell to other countries and to potential manufacturers.
Finally got my first shot of Pfizer on Sunday, bless my asthma and hypertension for placing me into the risk group! Felt nothing for a few hours, then fell asleep during our match against Leeds. Thought it was just how wank the game was but once I woke I was really cold and still sleepy. Only got a slight fever during the night and in the morning I felt like I was beaten with an iron rod all night Took a glass of whiskey with my morning coffee and fecked off back to bed. Yesterday I woke up feeling absolutely fantastic. My mom's a nurse so she has had two shots of AZ already, my dad will get his second shot of Pfizer next week. Can finally breathe easy and knowing we can watch the Euros together at their place soon makes me so happy!
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Hmm yeah good point. I was concerned that, as we were maybe starting to reach some of the younger people, we may see a bigger impact of the perceived vaccine skeptics in this country. Obviously there was a lot of polls ahead of the vaccination campaign and in the early days that showed relatively low numbers for people being willing to get vaccinated in France, but so far that doesn't seem to be reflected in the vaccine campaign.
As long as there is chaos and disagreement in "the West", Putin and his regime are happy. They must have been watching with absolute glee when the EU and the UK were engaged in a war of words because of AZ shortages.
Wife got moderna this morning. Sore arm so far.
told that’s what I will get tomorrow
told that’s what I will get tomorrow
State run misinformation campaign on social media. Classic. So fecking evil in this context.
UK Orders 60m Extra Pfizer Doses For Covid Booster Jabs
The booster programme is set to begin in the autumn. An extra 60m doses of the Pfizer/BioNTech vaccine have been secured by the government for Covid-19 booster jabs, Matt Hancock has announced.
The booster programme is set to begin in the autumn. An extra 60m doses of the Pfizer/BioNTech vaccine have been secured by the government for Covid-19 booster jabs, Matt Hancock has announced.
Is it the first dose?
Getting mine on Thurs
Yes. Her arm is killing her tonight but no fever or anything like that so far
I had both Moderna doses.
The first one only gave me pain in the arm but the second one was much worse unfortunately.
This story on how the Pfizer vaccine is made is incredibly interesting and also shows the sizable constraints on manufacturing an mRNA vaccine (namely all of the source DNA comes from one plant and is then sent to other plants for processing).
https://www.nytimes.com/interactive/2021/health/pfizer-coronavirus-vaccine.html
It seems the production of Sputnik is, somewhat unsurprisingly, a dumpster fire. As this thread explains, the Sputnik manufacturing process apparently didn't delete the gene controlling replication of the adenovirus so the Sputnik samples that Brazil and Slovakia have received are of vaccines that will replicate after injected.
https://www.nytimes.com/interactive/2021/health/pfizer-coronavirus-vaccine.html
It seems the production of Sputnik is, somewhat unsurprisingly, a dumpster fire. As this thread explains, the Sputnik manufacturing process apparently didn't delete the gene controlling replication of the adenovirus so the Sputnik samples that Brazil and Slovakia have received are of vaccines that will replicate after injected.
I have to get the first tomorrow
Are you feeling better now?
Yesterday i was better but it took 2 days of feeling unwell and night chills.
Although i may say that the vaccine doesn't effect everyone in the same way as some friends didn't have any symptoms while other swere much worse than me - same age group and same vaccine. Strange.
That's a really good article, and gives a nice handle on the timeline of the process - including those long pauses as the vaccine waits for quality tests to complete.
One of the documents from EMA that was leaked when they got hacked before Christmas gives an interesting "regulator's eye view" of the product. Their responsibility doesn't end once they've the clinical trial data. Their next job is to see if the manufactured product is the same as the product trialled (composition, concentration, integrity, contaminants) - and in the early Pfizer production it wasn't quite there. Ramping up from trial size batches to product is not easy:
https://www.bmj.com/content/372/bmj.n627
After the jabs - a survey of 627,383 people reporting their reactions/symptoms after their covid jabs. The most common side-effect was some pain or tenderness in the injected arm - more than half the recipients experienced that. The next most common was headache/fatigue - around a quarter of the group experienced that, typically mild and lasting a day or so.
Interestingly the reported real world rates are lower than the clinical trial reported rates.
https://www.bbc.co.uk/news/health-56901356
Interestingly the reported real world rates are lower than the clinical trial reported rates.
https://www.bbc.co.uk/news/health-56901356
Good news for UK, bad news for the rest of the world - not because of UK specifically, but I fear USA and EU will jump on this bandwagon pushing the third world even further behind. It's going to be sad to see the entire UK, EU and USA populations receiving their second Covid vaccines whilst a lot of the rest of the world is waiting for their first.
The EU has already made a massive order for booster doses, but from next year.
The UK needs to switch everybody over to Pfizer because it's easier to update for new variants and doesn't face vector immunity issues. Plus, it seems like it works better against new variants it's not been adapted for.
The key now is going to be how fast production can go up globally. Which in turn still depends a lot on J&J and AZ. Pfizer are already expecting to produce massively more vaccine doses than they originally planned, and have deals with people like Sanofi to do it.
By Q3/4 we should be seeing Novavax and Curevac - both of which have the potential to offer fridge temperature vaccines, and high production volumes. But like all potential, we won't know what we've really got until they're actually out there.
There are lots of other potentials out there as well. There's an intriguing Cuba/China project underway for example. If it can avoid some of the pitfalls of some of the other Chinese vaccines that could be a real boost to the world.
My own guess is that we'll see multiple countries including the UK and the US giving away (or simply postponing deliveries) of their excess supply during Q3 and that there will be a lot of vaccine doses available globally in Q4. Unfortunately that prediction depends on all the vaccines remaining acceptable (efficacy and safety).
It will end up a vicious cycle where the first world continually vaccinated themselves against new variants while the third world acts as a breeding ground for new variants.
First step to the Holy Grail completed. A vaccine that provides immunity against all coronaviruses. Will work against any and all future variants of SARS-COV-2 as well as any nasty new coronaviruses which might be brewing up in a pangolin’s arse in a jungle somewhere.
Apologies if this has already been answered, but have they said that those people who had the AZ vaccine will also be able to take the Pfizer booster shot or are they expected to wait for a AZ booster?
It's from UNC. The long and somewhat questionable New Yorker piece alleging a lab leak and worse in China also named some UNC labs (and Fauci) as being part of the dangerous research into viral diversity. I wonder if it's one of those labs.
It's thought that we'll be able to switch vaccines. They're trialling switching between dose 1 and 2 at the moment. They'll trial the same thing with boosters, first to check for safety, then for what happens to the antibodies.
What they're hoping to find is that we can switch brands/types and that we only need one booster jab per year.
Today was my vaccine trial visit #6 - I'm now officially fully vaccinated with Novavax. Over the past 6 months in the trial, I've also had two PCR covid tests, a couple of medical checkups, lots of blood pressure, temperature and pulse O2 checks and they've got 4 batches of blood for antibody testing.
I either received both doses of vaccine in November, and two doses of placebo this month - or I got the placebo in November and the real thing now. I think I had the vaccines in November, and that a bit of tenderness near the injection point was the only symptom I experienced - but that's a guess, I won't know until I get unblinded.
So where does that leave me on the vaccine passport game? Well, I've got an A4 certificate that lists all 4 jab dates and says that I've had a complete course of the vaccine. But it's a certificate for a vaccine that so far has no regulatory approval (not anywhere in the world) and it doesn't specify the real vaccination dates or give batch numbers (both of which are needed for my NHS record).
Assuming the vaccine gets MHRA approval, I'm told they're looking for a way to give us what we need for any sort of official app. That might mean them unblinding all of the trialists, or unblinding us as we request it, or something else - they haven't worked that bit out yet. They have asked us to stay blinded for "a couple more weeks at least" - so they can get the safety/reactions data while we're still in the blinded trial.
Vamos a ver.
I either received both doses of vaccine in November, and two doses of placebo this month - or I got the placebo in November and the real thing now. I think I had the vaccines in November, and that a bit of tenderness near the injection point was the only symptom I experienced - but that's a guess, I won't know until I get unblinded.
So where does that leave me on the vaccine passport game? Well, I've got an A4 certificate that lists all 4 jab dates and says that I've had a complete course of the vaccine. But it's a certificate for a vaccine that so far has no regulatory approval (not anywhere in the world) and it doesn't specify the real vaccination dates or give batch numbers (both of which are needed for my NHS record).
Assuming the vaccine gets MHRA approval, I'm told they're looking for a way to give us what we need for any sort of official app. That might mean them unblinding all of the trialists, or unblinding us as we request it, or something else - they haven't worked that bit out yet. They have asked us to stay blinded for "a couple more weeks at least" - so they can get the safety/reactions data while we're still in the blinded trial.
Vamos a ver.
Still very good news. I should be able to get an AZ shot in the next month so hanging out for them to open up for my age group.