SARS CoV-2 coronavirus / Covid-19 (No tin foil hat silliness please)

Another thing that is annoying, is I know of people who have covid and still go out shopping or to places and it's just crazy to me.

I've literally be in hibernation until I get my booster next week.
 
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Another thing that is annoying, is I know of people who have corvid and still go out shopping or to places and it's just crazy to me.

I've literally be in hibernation until I get my booster next week.
They must be stark raven mad.
 
One of my models I was due to shoot with on 27th ahead of her birthday, is now in isolation, she hasn't had any vaccinations either and probably won't either.

Hopefully she will be okay and ready for our studio shoot, which is more important in early January.

Those Warhammer modeling kits have really taken off. Hope it goes well.
 
Pinged each of last three days for close contact. LFT all confirm negative. Can’t wait to get out of London for a few days
 
I'm into my third day of symptoms today (had a positive pcr test yesterday) and feeling quite rough now

I'm starting to get a bit short of breathe which is worrying, but had an old asthma inhaler lying around which did the trick

Are there any over the counter treatments which can help? I guess just all the regular cold and flu stuff?
Not a regular reader of this thread but just dropped by and saw your post. Get the pulse oximeter already as suggested by someone and keep monitoring every few hours, especially since you already felt shortness of breath. Most likely it is mild but you should not wait till it gets worse. May also want to try the 6 min walk test.
 
I wonder how much of that is inherent and how much of that is vaccine driven relative to Delta. I think that’s a vital question as that’ll determine vaccine strategy going forward I think.
 
On Today some scientist said “game changing” anti-viral drugs were ready to go in about 2 weeks
 
Somehow managed to avoid covid and every variant thus far, had another narrow escape. Visiting the gf in DC and we had a small gathering at the apartment (they’re all vaccinated and boosted over there) last Friday and we flew to Cincinnati the next day. Find out today one of the girls at the party has tested positive and had to cancel her trip to Europe. Seems she was exposed after we left though.

Here’s to more narrow escapes.
 
Somehow managed to avoid covid and every variant thus far, had another narrow escape. Visiting the gf in DC and we had a small gathering at the apartment (they’re all vaccinated and boosted over there) last Friday and we flew to Cincinnati the next day. Find out today one of the girls at the party has tested positive and had to cancel her trip to Europe. Seems she was exposed after we left though.

Here’s to more narrow escapes.
You’ve probably had it without symptoms or had it earlier with minor symptoms and thought it was a cold / flu, you have anything early 2020 from Jan/Feb ?
 
I had awful, awful cough in February 2020 then few days later felt awful for about two hours whilst sat in pub. Then I felt fine. Maybe that was it.
 
I had awful, awful cough in February 2020 then few days later felt awful for about two hours whilst sat in pub. Then I felt fine. Maybe that was it.
A lot of people I know think they had it around that time.. for many it might have just been a cold etc but very likely a lot were also covid. My own opinion, it was probably floating around in the west from before Jan 2020, and many months in China before the Dr first raised the alarm
 
A girl I know has had a positive PCR last week and still been putting her child in nursery and been going out Christmas shopping and everything. Unbelievable.

I’ve managed to avoid covid, that I know of, although I did have a really bad chest for almost 6 months last year to the point I had X-rays and stuff done. I’m asthmatic but have never been that bad before or after, looks coincidental. Would be just my luck to go to the Trafford Centre tomorrow and catch it.
 
A girl I know has had a positive PCR last week and still been putting her child in nursery and been going out Christmas shopping and everything. Unbelievable.

I’ve managed to avoid covid, that I know of, although I did have a really bad chest for almost 6 months last year to the point I had X-rays and stuff done. I’m asthmatic but have never been that bad before or after, looks coincidental. Would be just my luck to go to the Trafford Centre tomorrow and catch it.
That's awful behaviour. Scum of the earth I'd go as far as.
 
Friend couldn't get a PCR test or a rapid test after having been in contact with a positive. PCR tests just out, while rapid tests only for symptomatic. She's in DC.
Of course, this destruction of inventory was months ago, but I'm imagining some planning could have prevented this.

 
Considering numerous experts are still - as of right now - not entirely convinced that omicron definitely causes milder disease than delta it’s a huge stretch to try and claim that the policy makers missed a trick by not assuming this was a certainty back when the decision was made to start boosting the younger cohorts.

And you also can’t divorce that decision from the ongoing delta wave, affecting all ages, at the time. Sure, the younger ages didn’t have all that much to fear from delta (although 0.2% hospitalisation rate is not to be sniffed at) but, again, these people weren’t living in a bubble.

And that’s without even getting into the tenuous upside of not boosting. That they will have better immunity next winter. It’s all about loading more and more immunity into the population, as safely and quickly as possible. Boosters are a no brainer in this context. There’s going to be an absolute shit-load of (almost all mild) breakthrough infections in the mix as well. That combination should leave us pretty well set for the next wave. And is far more acceptable to the public than choosing not to boost (with boosters available) and deliberately letting hundreds of thousands of people get avoidably unwell because there’s a possibility this might give them better long term immunity. I’ve known plenty of young(ish) vaccinated people get breakthrough infections that would be classified as “mild” who have felt like absolute shit and have taken a long time to recover (some of them still not fully over it) That’s really not a palatable choice to individuals if they could get a similar immune boost which gives them nothing worse than an achey delt for 24 hours.

Fair enough, I agree it's a stretch.

Other than our general risk tolerance / preference, I think the main place we diverge here is our assessment of vaccine efficacy. You're sure there's going to be a shit-load of breakthrough infections post-booster, and if that is the case then my entire argument is at least redundant, and probably stupid. Inevitably booster + mild infection would be better than 2nd dose + mild infection.

I'm much more optimistic that the booster will prevent infection in the short-term. I've just not seen the evidence that the risk of breakthrough infection post-booster is that high. We'll definitely find out soon!

Do we know how long the immunity lasts after the booster?

Not really, mostly for practical reasons. From the PHE study (pages 6-8) we saw immunity start to wane 10 weeks after the second dose, which echoes what they're saying now about the booster. We don't have much data after 10 weeks as the booster roll-out started properly in the beginning of October, 12 weeks ago.

While that makes for an interesting headline, it doesn't tell us much. Even though the level of protection against symptomatic disease started to drop 10 weeks after the 2nd dose, it didn't drop by much: for AZ it dropped from 65% to 60%, for Pfizer it dropped from 90% to 80%. And more importantly, protection against hospitalisation hardly dropped at all: from 95% to 90% for AZ, and from 98% to 96% for Pfizer (or thereabouts). Or as PHE put it:

In most groups there is relatively limited waning of protection against hospitalisation over a period of at least 5 months after the second dose.
When you get to 6 months the declines were more substantial after dose 2, and no-one in the UK has been boosted for that long. Israel might have some data on that but I've not seen any.

One other thing worth mentioning about the "immunity begins to wane after 10 weeks" headline is that we know immunity wanes quicker among more vulnerable populations, and it's the more vulnerable populations that got boosted first. So we should assume it'll wane slower for the general population than whatever the waning is now. And given how much the booster multiplied the number of antibodies, it's waning from a much higher bar so it seems reasonable to assume protection will last longer post-booster than post-dose 2. Even with Omicron's capacity for immune escape, from what I can tell. EDIT: Maybe not with Omicron.

It's worth saying that immunity isn't really a binary thing either, so there won't be a point that immunity will last until. There'll likely be some level of immune response for years to come from that second vaccine dose - that's what they saw post-MERS trials - it just becomes less effective as the volume of immune first responders (antibodies, B-cells, T-cells) declines. The dose of infection we get varies so a low-dose infection can still be fought off by a low-dose immune response.

The figures about waning immunity look at the average person with the average dose of infection, which is useful at the population level but less useful at the individual level. In other words we shouldn't think about those timings as cut-off points for when we suddenly stop being immune to covid, it's more complicated than that.
 
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I'm into my third day of symptoms today (had a positive pcr test yesterday) and feeling quite rough now

I'm starting to get a bit short of breathe which is worrying, but had an old asthma inhaler lying around which did the trick

Are there any over the counter treatments which can help? I guess just all the regular cold and flu stuff?

Sorry to hear that mate. I believe over the counter stuff is the usual advice. Have you had the booster yet? I'm guessing not. Look after yourself and get to hospital if you get serious breathing issues.
 
The report you linked is week 49, the week 51 is update is out now. Protection from infection is diminishing fairly quickly in the first boosted. A complication there, as always, is that the early boosters were given to the most vulnerable - oldest, clinically risk and to frontline healthcare - so it may not be as bad as it looks. Unfortunately by definition the highest risk groups are also amongst the ones becoming vulnerable again fastest, and we're already seeing hospitals lose a lot of their staff to positive tests.

https://www.gov.uk/government/publications/covid-19-vaccine-weekly-surveillance-reports

There's a good explanation of the data at:
 
A girl I know has had a positive PCR last week and still been putting her child in nursery and been going out Christmas shopping and everything. Unbelievable.

I’ve managed to avoid covid, that I know of, although I did have a really bad chest for almost 6 months last year to the point I had X-rays and stuff done. I’m asthmatic but have never been that bad before or after, looks coincidental. Would be just my luck to go to the Trafford Centre tomorrow and catch it.
Wouldn't that sort of negligence be criminal?
 
My elderly parent-in-laws arrived today from England for Christmas. Mother-in-law has tested positive in a LFT just now. No PCR slots available. Merry Christmas
 
Definitely not the case in London. Now or ever. It’s seething with middle aged folk acting like teenagers.

Just saw that 70% of NSW infections are in the 10-39 year cohort. Stated the this is driven by Christmas parties and nightclubs but no data provided to prove it. 80% of NSW infections are now Omicron so it wouldn't be surprising if packed venues were super-spreader events.
 
It's thought that the exposure to symptoms delay is shorter than for Delta - maybe between 3 and 7 days.

Take care guys. Try and have the best and safest Christmas you can.
The annoying thing is they paid a small fortune for flying to have a private PCR, which was negative but she says they only did the nose not the throat as well
 
The annoying thing is they paid a small fortune for flying to have a private PCR, which was negative but she says they only did the nose not the throat as well

It could just be that the viral load was so low that the test was negative due to being so early in the infection.
 
The report you linked is week 49, the week 51 is update is out now. Protection from infection is diminishing fairly quickly in the first boosted. A complication there, as always, is that the early boosters were given to the most vulnerable - oldest, clinically risk and to frontline healthcare - so it may not be as bad as it looks. Unfortunately by definition the highest risk groups are also amongst the ones becoming vulnerable again fastest, and we're already seeing hospitals lose a lot of their staff to positive tests.

https://www.gov.uk/government/publications/covid-19-vaccine-weekly-surveillance-reports

There's a good explanation of the data at:


Oh

In that case I agree @Pogue Mahone it seems likely a lot will be getting boosted + infected and my theory’s completely redundant:D
 
Here we go its getting closer to me. One of my sons friends (9) was here yesterday for a few hours and again today. They are in school together also. The friend just had a positive antigen. I took the feckers to the local football club that I manage today so we could play on the Astro. 20 mins in a car with him. Then he was here in the house for a couple hours

He's off to get a PCR tomorrow. Don't suppose there is such a thing as false positive!!

I've a slight tickly throat now and I'm paranoid!
 
Here we go its getting closer to me. One of my sons friends (9) was here yesterday for a few hours and again today. They are in school together also. The friend just had a positive antigen. I took the feckers to the local football club that I manage today so we could play on the Astro. 20 mins in a car with him. Then he was here in the house for a couple hours

He's off to get a PCR tomorrow. Don't suppose there is such a thing as false positive!!

I've a slight tickly throat now and I'm paranoid!
I dunno why, but you giving his age in brackets there made me laugh.
 
Here we go its getting closer to me. One of my sons friends (9) was here yesterday for a few hours and again today. They are in school together also. The friend just had a positive antigen. I took the feckers to the local football club that I manage today so we could play on the Astro. 20 mins in a car with him. Then he was here in the house for a couple hours

He's off to get a PCR tomorrow. Don't suppose there is such a thing as false positive!!

I've a slight tickly throat now and I'm paranoid!
Join the club. Feck it. Good luck to you