SARS CoV-2 coronavirus / Covid-19 (No tin foil hat silliness please)

This week vs last week (county by county in SC)



Updated numbers...



My district announced that we’re going to 75% capacity (rotating 4 day schedule for the kids, 5 days for the teachers) starting after winter break.

Here’s last week for comparison...

 
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so what is this magic drug that got Guliani up from his death bed within days?
If it's the same treatment that Trump got, it's probably antibodies from recovering patients who volunteered to share it. Which, as you can see, is extremely rare.

Dexamethasone as well is shown to be effective at preventing the more severe cases as well. Cheaper and more common. But not the same level as the antibodies.

The former New York mayor said he received remdesivir, dexamethasone and “exactly the same” treatment that Trump got in October when he was hospitalized, which the president has often credited for his speedy recovery.

https://www.washingtonpost.com/poli...oronavirus-treatments-many-are-dying-without/
 
3000 deaths a day!! :wenger: :eek: I'm just struggling to get my head around that in a poor African country for any reason let alone in the USA. That's 30,000 new deaths in 10 days. :( And it's 300,000 new deaths in just over three months.

Shiieeeet. I know lots die due to cancer, malaria, even alcohol/drug/nicotine abuse, but to die in that number because of simply not wearing a mask and keeping some social distance is mind numbing. What other species on earth goes through such mass suicide/murder? Lemmings? Surely, that's just a myth too.

Especially when capitalist giants like Goldman Sachs are saying dude, you need to wear a mask so we can keep making those stacks. It will be looked back on as one of the biggest symbols of the US failing to lead by example on the global stage once more. And presumably hailed by libertarians for decades as a great moment, contrary to all available evidence.

https://www.goldmansachs.com/insights/pages/face-masks-and-gdp.html
 
Germany's situation has been worsening this past month. Starting to look like other countries in Europe now.
BIG33wk.jpg
 
Germany's situation has been worsening this past month. Starting to look like other countries in Europe now.
People have given up, we should have had proper lockdowns to begin with. It's dragged on for nearly a year when it could have been so easily stopped. No point in adding stricter rules for people to ignore.
 
Anyone know why the UK have changed their post travel isolation policy from 14 days to 10? It did seem odd to me that people known to be in contact with someone infected isolated for 10 days, based on the incubation and infection period, but the travel one was different. What was the supposed logic underpinning it then, and what is it now?

I rented somewhere away from the family home for the full 14 days, happy enough to do that given those were the rules I'd agreed to when I left, but it is a bit annoying throwing a couple of hundred quid down the drain...
 
Anyone know why the UK have changed their post travel isolation policy from 14 days to 10? It did seem odd to me that people known to be in contact with someone infected isolated for 10 days, based on the incubation and infection period, but the travel one was different. What was the supposed logic underpinning it then, and what is it now?

I rented somewhere away from the family home for the full 14 days, happy enough to do that given those were the rules I'd agreed to when I left, but it is a bit annoying throwing a couple of hundred quid down the drain...
It assumes that you've had no symptoms during the ten days and that you're isolating throughout. Hence your last possible infection contact is ten days ago. People generally start showing symptoms around 5 days +/- 2 and are at their most infectious in the couple of days before, through to about 3/5 days after.

The ten days then covers the idea of: "typical 5 day" to symptoms + 5 days days after, or 7 days to symptoms + 3 after pattern from which they suggest that should also cover all the asymptomatic cases. That's the basic rationale. It's also why they're giving travellers the option of a (paid for) test after 5 days, with a possibility of early release.

The clock restarts if you do get symptoms, at which point you need a test.
 
Germany's situation has been worsening this past month. Starting to look like other countries in Europe now.
BIG33wk.jpg

I see that in my village. Some days ago there was the message of first cases in the care home. A week later 43 of 80 older people tested positive, 6 are in hospital, 3 are already dead. 18 of the staff tested positive, too. And that is just the start of it as the first cases were just found a week ago.

My parents bought an apartment in the new house of the organisation a year ago where they offer day care for older people (for people in the appartments that need it but from the outside, too and all kind of help as needed (from housekeeping to meals to body care etc.). Everybody who lives there got tested but fortunately all negative - atleast until now (Keep your fingers crossed, please!)
 
Worrying for the UK is cases are rising again, 21672 today and hospital admissions rising to 1622.

After the Nov-Dec restrictions, cases came down to 14k from a peak of 24k and admissions down to 1200 from 2k
 
3000 deaths a day!! :wenger: :eek: I'm just struggling to get my head around that in a poor African country for any reason let alone in the USA. That's 30,000 new deaths in 10 days. :( And it's 300,000 new deaths in just over three months.

Shiieeeet. I know lots die due to cancer, malaria, even alcohol/drug/nicotine abuse, but to die in that number because of simply not wearing a mask and keeping some social distance is mind numbing. What other species on earth goes through such mass suicide/murder? Lemmings? Surely, that's just a myth too.

Once big orange man politized it, it was going to be downhill until we get to an obscene number. Add that with our selfishness... going to be a long few months.
 
Cases on the up, R rate on the up...and this time next week, bars, restaurants and pubs will have been given the green light to re-open, and then the easing up of the rules.

It's going to get significantly worse before it gets better
 
Another of those science wow moments, this time from researchers looking for potential treatments by analysing the DNA of thousands of covid ICU patients. They've already identified 5 genes that were seen more often in the ICU patients than in a matching healthy control group. That in turn has allowed them to identify some existing drugs that may be worth prioritisation as part of the ongoing treatment clinical trials.

https://www.theguardian.com/science...sts-identify-drugs-that-may-help-severe-cases
 
One of my favourite walks when I lived there :(

When I was walking over Tower Bridge a Chinook flew directly over probably only 15m above the bridge, which was pretty cool but also emphasised the whole eary feeling of being in some kind of oppressive regime reality. The police stopping and searching half the people on the bridge didn't exactly help either, although I presume there was a non covid related reason why that was happening.

Have to say although I don't agree with these anti lockdown protests at all, I can see how people feel like their freedoms are being taken away and end up feeling really anxious about it. It's quite scary how dead everything is.

Also the trains are still a big problem. Even in an empty city they're still pretty packed. I did think it was silly not having any outdoor christmas markets or things that are minimal risk to cheer people up, but the problem would be that they'd draw so many people and then the trains/transport would also then be a much bigger problem.

I don't really see the point in delaying the tier 3 decision if it's basically inevitable. I also don't get why they can't just close the schools a week early for Christmas. I'm strongly for keeping them open in general as fair education is vitally important, but the last week of term before Christmas is hardly peak learning time, and supposedly the rates are rising most rapidly among school ages.
 
It assumes that you've had no symptoms during the ten days and that you're isolating throughout. Hence your last possible infection contact is ten days ago. People generally start showing symptoms around 5 days +/- 2 and are at their most infectious in the couple of days before, through to about 3/5 days after.

The ten days then covers the idea of: "typical 5 day" to symptoms + 5 days days after, or 7 days to symptoms + 3 after pattern from which they suggest that should also cover all the asymptomatic cases. That's the basic rationale. It's also why they're giving travellers the option of a (paid for) test after 5 days, with a possibility of early release.

The clock restarts if you do get symptoms, at which point you need a test.

Yeah I understood the rationale behind the 10 day period, but not the rationale between switching between 14 and 10. I had thought that by day 10, if you've had no symptoms you can be sure you will not transmit the virus as a symptomatic or asymptomatic carrier.

After reading the CDC reports it turns out a minority of people develop symptoms on day 12, and so theoretically could be at their most infectious in days 10-14. So the previous travel guidelines of 14 days wasn't nonsensical but just exceptionally cautious. Fair enough. Still seems a little strange to me that they'd change these guidelines now when the evidence doesn't seem to have changed.

Another of those science wow moments, this time from researchers looking for potential treatments by analysing the DNA of thousands of covid ICU patients. They've already identified 5 genes that were seen more often in the ICU patients than in a matching healthy control group. That in turn has allowed them to identify some existing drugs that may be worth prioritisation as part of the ongoing treatment clinical trials.

https://www.theguardian.com/science...sts-identify-drugs-that-may-help-severe-cases

Very cool.
 
Had my vaccine on Thursday. I always react badly to vaccines, but it felt as if the peak of my COVID hit me in one evening. I felt terrible. I’m back to normal now though. I’ve had COVID twice already and I’d say my reaction was the worst I’ve felt.

Nevertheless, take the vaccine when it’s offered to you.

My thoughts over the last few weeks:
  1. We’re seeing an increase of fungal infections post COVID. I’ve seen a few cases now of patients recovering from COVID, but then deteriorate quickly while still being in hospital. Increased oxygen requirement. Treated with strong antibiotics in case it’s a bacterial pneumonia on top (Meropenem for those interested). Does nothing. Chest X-ray appears worse, and a fungal blood test given its appearance comes back positive. I’ve personally seen three cases now, and I’m hearing a few of my colleagues seeing more. Wouldn’t be surprise to see an article on this soon.
  2. Still a lot of death, and my “high dependency COVID” ward is now jam packed again. ITU are completely full so unfortunately we’ve had patients die because they are in no position to be transferred and there is no where in the hospital to be safely intubated and cared for. Yesterday alone I had to do 4 family phone calls explaining to them that they are unfortunately dying and our treatment has not worked and that we’d be turning our focus to keeping their loved one comfortable. I was depressed as feck by the end of yesterday.
  3. Starting to see some benefit from the use of methylprednisalone according to my ITU colleagues. Still early days but hopefully it’ll be something that is explored more.
 
Had my vaccine on Thursday. I always react badly to vaccines, but it felt as if the peak of my COVID hit me in one evening. I felt terrible. I’m back to normal now though. I’ve had COVID twice already and I’d say my reaction was the worst I’ve felt.

Nevertheless, take the vaccine when it’s offered to you.

My thoughts over the last few weeks:
  1. We’re seeing an increase of fungal infections post COVID. I’ve seen a few cases now of patients recovering from COVID, but then deteriorate quickly while still being in hospital. Increased oxygen requirement. Treated with strong antibiotics in case it’s a bacterial pneumonia on top (Meropenem for those interested). Does nothing. Chest X-ray appears worse, and a fungal blood test given its appearance comes back positive. I’ve personally seen three cases now, and I’m hearing a few of my colleagues seeing more. Wouldn’t be surprise to see an article on this soon.
  2. Still a lot of death, and my “high dependency COVID” ward is now jam packed again. ITU are completely full so unfortunately we’ve had patients die because they are in no position to be transferred and there is no where in the hospital to be safely intubated and cared for. Yesterday alone I had to do 4 family phone calls explaining to them that they are unfortunately dying and our treatment has not worked and that we’d be turning our focus to keeping their loved one comfortable. I was depressed as feck by the end of yesterday.
  3. Starting to see some benefit from the use of methylprednisalone according to my ITU colleagues. Still early days but hopefully it’ll be something that is explored more.

Its a tough read but well done for all you are doing. It boils my blood that people like you are dealing with shit like this on a daily basis and people think it’s a good idea to arrange maskless marches in protest of their reduced lib-urh-tees.
 
Worrying for the UK is cases are rising again, 21672 today and hospital admissions rising to 1622.

After the Nov-Dec restrictions, cases came down to 14k from a peak of 24k and admissions down to 1200 from 2k

I'm not surprised. I've been back a week and it's so relaxed compared to continental Europe. Coming though France the roads were virtually empty but driving up from Dover it was like a normal day. I'm quarantined in a Tier 2 area and looking out of the window, seems like I'm the only one who cares.
 
When I was walking over Tower Bridge a Chinook flew directly over probably only 15m above the bridge, which was pretty cool but also emphasised the whole eary feeling of being in some kind of oppressive regime reality. The police stopping and searching half the people on the bridge didn't exactly help either, although I presume there was a non covid related reason why that was happening.

Have to say although I don't agree with these anti lockdown protests at all, I can see how people feel like their freedoms are being taken away and end up feeling really anxious about it. It's quite scary how dead everything is.

Also the trains are still a big problem. Even in an empty city they're still pretty packed. I did think it was silly not having any outdoor christmas markets or things that are minimal risk to cheer people up, but the problem would be that they'd draw so many people and then the trains/transport would also then be a much bigger problem.

I don't really see the point in delaying the tier 3 decision if it's basically inevitable. I also don't get why they can't just close the schools a week early for Christmas. I'm strongly for keeping them open in general as fair education is vitally important, but the last week of term before Christmas is hardly peak learning time, and supposedly the rates are rising most rapidly among school ages.
Welcome to everyday life during many years growing up in NI
 
Had my vaccine on Thursday. I always react badly to vaccines, but it felt as if the peak of my COVID hit me in one evening. I felt terrible. I’m back to normal now though. I’ve had COVID twice already and I’d say my reaction was the worst I’ve felt.

Nevertheless, take the vaccine when it’s offered to you.

My thoughts over the last few weeks:
  1. We’re seeing an increase of fungal infections post COVID. I’ve seen a few cases now of patients recovering from COVID, but then deteriorate quickly while still being in hospital. Increased oxygen requirement. Treated with strong antibiotics in case it’s a bacterial pneumonia on top (Meropenem for those interested). Does nothing. Chest X-ray appears worse, and a fungal blood test given its appearance comes back positive. I’ve personally seen three cases now, and I’m hearing a few of my colleagues seeing more. Wouldn’t be surprise to see an article on this soon.
  2. Still a lot of death, and my “high dependency COVID” ward is now jam packed again. ITU are completely full so unfortunately we’ve had patients die because they are in no position to be transferred and there is no where in the hospital to be safely intubated and cared for. Yesterday alone I had to do 4 family phone calls explaining to them that they are unfortunately dying and our treatment has not worked and that we’d be turning our focus to keeping their loved one comfortable. I was depressed as feck by the end of yesterday.
  3. Starting to see some benefit from the use of methylprednisalone according to my ITU colleagues. Still early days but hopefully it’ll be something that is explored more.
Thank you & to the other medical staff etc posting here. It sounds horrendous, and like @Pexbo said below it makes my blood boil that a percentage of society choose to ignore or dismiss it. It’s depressing actually
 
Yeah I understood the rationale behind the 10 day period, but not the rationale between switching between 14 and 10. I had thought that by day 10, if you've had no symptoms you can be sure you will not transmit the virus as a symptomatic or asymptomatic carrier.

After reading the CDC reports it turns out a minority of people develop symptoms on day 12, and so theoretically could be at their most infectious in days 10-14. So the previous travel guidelines of 14 days wasn't nonsensical but just exceptionally cautious. Fair enough. Still seems a little strange to me that they'd change these guidelines now when the evidence doesn't seem to have changed.



Very cool.

This analysis was published in Ireland recently. They reckon about 85% of symptomatic cases will have symptoms by day 10. 95% by day 14. Which doesn’t seem to have changed from earlier analyses. It does seem a bit foolhardy to me to deliberately allow 10% of cases stop self isolating before they have symptoms.
 
This analysis was published in Ireland recently. They reckon about 85% of symptomatic cases will have symptoms by day 10. 95% by day 14. Which doesn’t seem to have changed from earlier analyses. It does seem a bit foolhardy to me to deliberately allow 10% of cases stop self isolating before they have symptoms.

They've been worried throughout that people aren't isolating when they're supposed to, and a shorter isolation period has been oft cited as a way that might make people do it. The trade off obviously is that a greater number of people properly self isolating when it's most important is worth missing some transmission at the end.

I'm not at all qualified to say whether that's sensible or daft, but I'm sure that's the thinking.
 
They've been worried throughout that people aren't isolating when they're supposed to, and a shorter isolation period has been oft cited as a way that might make people do it. The trade off obviously is that a greater number of people properly self isolating when it's most important is worth missing some transmission at the end.

I'm not at all qualified to say whether that's sensible or daft, but I'm sure that's the thinking.

Actually, that’s a fair point.
 
This analysis was published in Ireland recently. They reckon about 85% of symptomatic cases will have symptoms by day 10. 95% by day 14. Which doesn’t seem to have changed from earlier analyses. It does seem a bit foolhardy to me to deliberately allow 10% of cases stop self isolating before they have symptoms.

Good info, cheers! I do think the 14 days was just too long for the majority so there had to be a trade-off between the medical science and the behavioural science. My main concern was my pregnant sister, so between days 10-14 I'll go back to the family home but play it safe for an extra few days regardless of the legal change.
 
Encountered a little Covid conspiracy march today in central Bournemouth. Always good for cheap amusement.
 
Tested positive. Did the test as a precaution on Wednesday. Started feeling some aches last weekend and decided to do it. Also, body temp got a bit higher and my coughing increased. (I have a coughing issue that predates covid. The meds I used didn't mesh with me so I stopped. Gonna eventually get a second opinion for different meds for that once I deal with this.

Only major issue I've had really is Thursday night/Friday morning when I had pain in my chest that lasted about 4 hours. It ebbed between dull uncomfortableness and then sometimes felt heavy. Not like I was gonna die or anything but painful. So it's mostly been joint pain, coughing and low grade fever. If I'm only coughing by this time next weekend I should be good to go I hope.
 
This analysis was published in Ireland recently. They reckon about 85% of symptomatic cases will have symptoms by day 10. 95% by day 14. Which doesn’t seem to have changed from earlier analyses. It does seem a bit foolhardy to me to deliberately allow 10% of cases stop self isolating before they have symptoms.

Foolhardy? Sounds truly idiotic to me.
 
I’ve had COVID twice already and I’d say my reaction was the worst I’ve felt.

Were you tested both times and how long between the two events?

Given the relative lack of documented asws of reinfections you might be a useful case study for researchers.
 
Had my vaccine on Thursday. I always react badly to vaccines, but it felt as if the peak of my COVID hit me in one evening. I felt terrible. I’m back to normal now though. I’ve had COVID twice already and I’d say my reaction was the worst I’ve felt.

Nevertheless, take the vaccine when it’s offered to you.

My thoughts over the last few weeks:
  1. We’re seeing an increase of fungal infections post COVID. I’ve seen a few cases now of patients recovering from COVID, but then deteriorate quickly while still being in hospital. Increased oxygen requirement. Treated with strong antibiotics in case it’s a bacterial pneumonia on top (Meropenem for those interested). Does nothing. Chest X-ray appears worse, and a fungal blood test given its appearance comes back positive. I’ve personally seen three cases now, and I’m hearing a few of my colleagues seeing more. Wouldn’t be surprise to see an article on this soon.
  2. Still a lot of death, and my “high dependency COVID” ward is now jam packed again. ITU are completely full so unfortunately we’ve had patients die because they are in no position to be transferred and there is no where in the hospital to be safely intubated and cared for. Yesterday alone I had to do 4 family phone calls explaining to them that they are unfortunately dying and our treatment has not worked and that we’d be turning our focus to keeping their loved one comfortable. I was depressed as feck by the end of yesterday.
  3. Starting to see some benefit from the use of methylprednisalone according to my ITU colleagues. Still early days but hopefully it’ll be something that is explored more.

Total respect for you and your coworkers, man. The bit about talking to dying families is disheartening. I just wouldn't know what to say and do.
 
Had my vaccine on Thursday. I always react badly to vaccines, but it felt as if the peak of my COVID hit me in one evening. I felt terrible. I’m back to normal now though. I’ve had COVID twice already and I’d say my reaction was the worst I’ve felt.

Nevertheless, take the vaccine when it’s offered to you.

My thoughts over the last few weeks:
  1. We’re seeing an increase of fungal infections post COVID. I’ve seen a few cases now of patients recovering from COVID, but then deteriorate quickly while still being in hospital. Increased oxygen requirement. Treated with strong antibiotics in case it’s a bacterial pneumonia on top (Meropenem for those interested). Does nothing. Chest X-ray appears worse, and a fungal blood test given its appearance comes back positive. I’ve personally seen three cases now, and I’m hearing a few of my colleagues seeing more. Wouldn’t be surprise to see an article on this soon.
  2. Still a lot of death, and my “high dependency COVID” ward is now jam packed again. ITU are completely full so unfortunately we’ve had patients die because they are in no position to be transferred and there is no where in the hospital to be safely intubated and cared for. Yesterday alone I had to do 4 family phone calls explaining to them that they are unfortunately dying and our treatment has not worked and that we’d be turning our focus to keeping their loved one comfortable. I was depressed as feck by the end of yesterday.
  3. Starting to see some benefit from the use of methylprednisalone according to my ITU colleagues. Still early days but hopefully it’ll be something that is explored more.
#1 got covered in Indian media today. What is the incidence rate? It said 5 people in a hospital here developed a fungal infection and 2 died.
 
Were you tested both times and how long between the two events?

Given the relative lack of documented asws of reinfections you might be a useful case study for researchers.

First was in March/April time, second was mid-October - and yes tested twice.

You’ll be surprised. We’ve had a few cases of double infections to be honest. Not as uncommon as it’s made out on media. I’m definitely not saying we’re seeing more and more re-infected as that would be a lie. But there were a few staff members before me, and I’ve managed maybe two patients with a second infection.

#1 got covered in Indian media today. What is the incidence rate? It said 5 people in a hospital here developed a fungal infection and 2 died.

That was quick! Difficult to say as I think its literally in the last week that we came to test it and found them to be positive. Which then begs the question of how many of the previous cases we had seen with a strange pattern of COVID deterioration was actually a susceptible fungal infection hitting someone while their immune was temporarily weakened.

A friend of mine said that after she had COVID, she had about two to three weeks of vaginal thrush straight after it, which is typically fungal (this was mid-October time too). At the time, I definitely didn’t make the connection because she said she was prone to getting them every now and then - but she did say this was the worst case she had.
 
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Had my vaccine on Thursday. I always react badly to vaccines, but it felt as if the peak of my COVID hit me in one evening. I felt terrible. I’m back to normal now though. I’ve had COVID twice already and I’d say my reaction was the worst I’ve felt.

Nevertheless, take the vaccine when it’s offered to you.

My thoughts over the last few weeks:
  1. We’re seeing an increase of fungal infections post COVID. I’ve seen a few cases now of patients recovering from COVID, but then deteriorate quickly while still being in hospital. Increased oxygen requirement. Treated with strong antibiotics in case it’s a bacterial pneumonia on top (Meropenem for those interested). Does nothing. Chest X-ray appears worse, and a fungal blood test given its appearance comes back positive. I’ve personally seen three cases now, and I’m hearing a few of my colleagues seeing more. Wouldn’t be surprise to see an article on this soon.
  2. Still a lot of death, and my “high dependency COVID” ward is now jam packed again. ITU are completely full so unfortunately we’ve had patients die because they are in no position to be transferred and there is no where in the hospital to be safely intubated and cared for. Yesterday alone I had to do 4 family phone calls explaining to them that they are unfortunately dying and our treatment has not worked and that we’d be turning our focus to keeping their loved one comfortable. I was depressed as feck by the end of yesterday.
  3. Starting to see some benefit from the use of methylprednisalone according to my ITU colleagues. Still early days but hopefully it’ll be something that is explored more.
Have you heard about the MATH+ Protocol created by the Frontline Covid 19 Critical Care Alliance? They're a group of experts with 2,000 papers between them, their Dr. Kory had testified on behalf of the group to the Senate months ago about the benefits of steroids which was adopted more widely, and just testified about recent studies showing remarkable results with ivermectin and standard care.

In his testimony he mentioned a Dr. Hector Carvallo in Argentina heading their coronavirus response, who used ivermectin nasal sprays as a prophylaxis for 800 healthcare workers and 0 got ill, while 400 that weren't treated had 237 healthcare workers getting sick.

Here's a link to their protocol and a 10 minute excerpt from the testimony of him begging the FDA to look at their presentation of the new data. Apologies it's a Fox feed, but it's just a live feed without commentary.

https://www.evms.edu/media/evms_pub...cine/EVMS_Critical_Care_COVID-19_Protocol.pdf