Oh yeah, for sure. I expect us to use all of them fairly regularly according to the situation. Mata & Mikhi are better at breaking stubborn teams down for example, whilst Rash and Martial are more effective running at teams that are more open. So whilst we're using this approach of one wide runner and one clever playmaker on the wings, I'd let Martial take the lead on current form, and give Rash the chance to come on late and punish the oppositions tiredness.
Both have a tendency to hold onto it too long but Rashford moreso, so I think he'd be better served with the 'easier' late shift, especially as Martial's killer instinct is better at present.
I'm happy with the variety of our options tbf. We could ideally do with a really good Beckham-esque crosser to cover all the bases, but I've never been entirely convinced Persisic would be that missing piece. He seems more like a more mature version of what we already have.