A bunch of polls out today, national general election polling.
Clinton is at least 3 points down on every single R challenger including Trump (-3: Fiorina, -4: Bush, -5: Trump, -11: Carson). I don't recall Obama's numbers ever being this bad in 2012. This doesn't even include Rubio who was beating Clinton at her peak.
Biden is ahead on every head-to-head, so it's not a anti-Democrat wave. Sanders wasn't polled but the last time he was he seemed to be doing better than her. It's looking more and more likely that Republicans will win the general, she seems quite hated nation-wide.
Another interesting trend I've seen is that her numbers go down in every early state, the more she is visible, the less she is supported.