I wouldn't worry too much about the bench if you have a good XI. Almost everyone will Wildcard before GW10, so there is unlikely to be too much rotation from CL teams, and even if there is, the likes of Jota and Foden will 90% of be subbed on (especially with 5 subs) meaning your bench player doesn't even get on. You have your weekly transfer for injuries etc... If you have a 4.5 playing midfielder (e.g. Andreas) I personally think that is fine for the start of the season.
Even if the worst does happen and you need to call on your second sub, is Neco Williams really going to be the difference in rank?
On the teams, I'm not a fan of the strikers you added personally. Things could change but I feel Jota is too much of a minutes risk for the price, there is a solid chance of him not starting games and getting 10-30 minutes (and when he does start, he is unlikely to finish) if we assume things won't change too much from last season. You need to start Edouard against Liverpool, Man City and Arsenal in the first 5, also not guaranteed a start.