The vaccines | vaxxed boosted unvaxxed? New poll

How's your immunity looking? Had covid - vote twice - vax status and then again for infection status

  • Vaxxed but no booster

  • Boostered

  • Still waiting in queue for first vaccine dose

  • Won't get vaxxed (unless I have to for travel/work etc)

  • Past infection with covid + I've been vaccinated

  • Past infection with covid - I've not been vaccinated


Results are only viewable after voting.
Interesting update from Denmark:



Good news for highly vaxxed countries.
 
Why am I not surprised that @Beans has not replied to above.
Sorry I've been busy. I wanted to find more of the studies I've seen cited. Found one that's a preprint and that's also being questioned. Are there usually so many questioned studies? Is there some kind of conspiracy to make ivermectin look effective? Could be.

I'm not saying I know the answers, and if all the stuff I've seen had been discredited, and that discrediting stands up over time, I'll happilly accept it all.

If I can get myself to do it I'll look for more of the data I've seen.

But yes, Merck say it doesn't work, right? Maybe they're right!
 
Sorry I've been busy. I wanted to find more of the studies I've seen cited. Found one that's a preprint and that's also being questioned. Are there usually so many questioned studies? Is there some kind of conspiracy to make ivermectin look effective? Could be.

I'm not saying I know the answers, and if all the stuff I've seen had been discredited, and that discrediting stands up over time, I'll happilly accept it all.

If I can get myself to do it I'll look for more of the data I've seen.

But yes, Merck say it doesn't work, right? Maybe they're right!

Not to mention why would it be a surprise that a horse dewormer wasn't a cure for covid?
 
Only 57%? :eek:
Yep. 62% of the adult population have had at least one dose, and around 57% have had a full course (that's about half of the whole population of the state). A tragedy in a country where vaccines have been freely available for months.

When you look at the hospitalisation stats it looks like someone is running a massively unethical clinical trial. When you look at ICU cases and deaths, you start to see the move into older age groups and more serious comorbidities - where vax take-up was higher, but not high enough.
 
Not to mention why would it be a surprise that a horse dewormer wasn't a cure for covid?
Is a medicine that's been used by humans for a while, it's a good one, and finding new purposes for old medicines is, as we say in the States, a thing.
 
Is a medicine that's been used by humans for a while, it's a good one, and finding new purposes for old medicines is, as we say in the States, a thing.

But rare the a drug is a treatment for something completely unconnected to its original purpose.
 
It seems like potentially important information, if it all turns out to be fake studies then sorry for wasting everyone's time, it seemed worth the ridicule to share the info I found. Normally I don't bother, because there are so many rude posters on here.
 
Not 100% sure but I think not. Wasn't anti vaxx or anything.

He has passed away since I initially posted. His wife had given birth to a son whilst he was in a coma. Gutted as he was such a nice and humble guy.

Regarding the vaccine, AZ in particular, there is a radio personality who died after having it. I mentioned another guy who has had a stroke and blood clots and my own mother passed away 6 months ago from stroke after the AZ jab.

Sorry to hear :(

Strange that AZ is still being used, Norway gave all we had of it away because of blod clot.
We just use Pfizer and Moderna.
 
A summary of bad news from Covax. Covax are supposed to be the main source of vaccines for whole chunks of the world. They're now expecting to receive only limited supplies in 2021.

Part of the story is vaccine hoarding by the rich (including stock that is having to be destroyed as it's reached its use by date). Which has now turned into another round of stockpiling in case boosters are needed.

The other issues mostly relate to the difficulty of scaling up production. Pfizer has been the only company that actually managed to scale up, more or less on plan.

 
A summary of bad news from Covax. Covax are supposed to be the main source of vaccines for whole chunks of the world. They're now expecting to receive only limited supplies in 2021.

Part of the story is vaccine hoarding by the rich (including stock that is having to be destroyed as it's reached its use by date). Which has now turned into another round of stockpiling in case boosters are needed.

The other issues mostly relate to the difficulty of scaling up production. Pfizer has been the only company that actually managed to scale up, more or less on plan.



Hopefully there are no new setbacks for Sanofi, the introduction of their vaccine could make a big difference for the rest of the world.
 
And what that lack of vaccines means in practice, even in a country like SA, which has been able to get some supplies.

In Western Cape they've been able to vaccinate about 38% of their 60+ group:

 
Sorry I've been busy. I wanted to find more of the studies I've seen cited. Found one that's a preprint and that's also being questioned. Are there usually so many questioned studies? Is there some kind of conspiracy to make ivermectin look effective? Could be.

I'm not saying I know the answers, and if all the stuff I've seen had been discredited, and that discrediting stands up over time, I'll happilly accept it all.

If I can get myself to do it I'll look for more of the data I've seen.

But yes, Merck say it doesn't work, right? Maybe they're right!

No, there's usually not this many discredited studies.

It's not a conspiracy. It's a simple grift IMO. Exploiting the more right wing people, exploiting their desire to stick one of the left and mainstream media/science. For example there quite a few doctos/Healthcare professionals who prescribe ivermectin for covid on request for a certain fee. And then right wing media drives this narrative of Ivermectin because they are contrarian to science.

One of the arguments put forth by these people is its the big pharma controlling things again, driving treatment to expensive meds and vaccine. Obviously that argument breaks down when Merkc (a big pharma) itself recommends against ivermectin. And then you have people like the FL governor acting like a spokesperson for Regeneron antibody cocktail instead of talking about vaccines. Guess who is big pharma now?
 
Rich countries stockpiling vaccines then having to destroy them because they`ve reached their use by date then stockpiling more in case boosters are needed.That is fecked up.
 
I can’t believe how many people (including many intelligent ones) have come out with the stat about how the majority of hospital covid cases are people who have been vaccinated. They are somehow using this fact to question whether the vaccine even works!

Surely, that many people can’t be bad at maths and percentages?! It’s pretty obvious most cases would be vaccinated considering there aren’t many unvaccinated adults left!
 
Had my second does of moderna yesterday, last time had no side effects just a sore arm. After I had the jab yesterday I was fine for most of the day but during the night I had shivers/high temp and couldn't sleep. Hopefully means the vaccine is working effectively.
 
Study done only in the US. But interesting when considering vaccine for teenagers.

Boys more at risk from Pfizer jab side-effect than Covid, suggests study
US researchers say teenagers are more likely to get vaccine-related myocarditis than end up in hospital with Covid
https://www.theguardian.com/world/2...zer-jab-side-effect-than-covid-suggests-study

The big red flag problem in the above is their definition of myocarditis based off terms and troponin in VAERS. That's not how myocarditis is diagnosed. Anyone can report anything in VAERS. There needs to be better analysis of these reports before saying they are actual myocarditis. This paper fails on that count.



 
Study done only in the US. But interesting when considering vaccine for teenagers.

Boys more at risk from Pfizer jab side-effect than Covid, suggests study
US researchers say teenagers are more likely to get vaccine-related myocarditis than end up in hospital with Covid
https://www.theguardian.com/world/2...zer-jab-side-effect-than-covid-suggests-study

Bit of a misleading headline. More at risk of being hospitalised by covid than the extremely rare side effect (which may or may not put them in hospital) It’s hard to get an accurate incidence of very rare outcomes anyway. So nobody can claim with any certainty that extremely rare outcome A is definitely more common than very rare outcome B.

Some important points in the tweets shared by @mav_9me too.
 
Had my second does of moderna yesterday, last time had no side effects just a sore arm. After I had the jab yesterday I was fine for most of the day but during the night I had shivers/high temp and couldn't sleep. Hopefully means the vaccine is working effectively.

Had mine Tuesday evening, felt pretty terrible by Wednesday lunchtime. Headache, dizziness, shivers and a general “fluey” feeling. It passed quite quickly though, by Thursday I felt ok again.
 
Had mine Tuesday evening, felt pretty terrible by Wednesday lunchtime. Headache, dizziness, shivers and a general “fluey” feeling. It passed quite quickly though, by Thursday I felt ok again.
Good to hear that mate.

Feeling a lot better now, so hopefully back to normal tomorrow with a good nights rest.
 


This is the inactivated virus vaccine that was going to be made in Livingstone.

I'm not sure if this is about timescales being pushed back, or if something has gone wrong with that factory project. Either way, not great news for Valneva who had been looking at modifying their vaccine to target variants. The vaccine is at phase 3 trials right now.

I think this is the trial that @lynchie was on - not sure if he still is.
 


This is the inactivated virus vaccine that was going to be made in Livingstone.

I'm not sure if this is about timescales being pushed back, or if something has gone wrong with that factory project. Either way, not great news for Valneva who had been looking at modifying their vaccine to target variants. The vaccine is at phase 3 trials right now.

I think this is the trial that @lynchie was on - not sure if he still is.


Wonder if this form of vaccination will become forgotten, with the success of the MRNA vaccines and the technology and the ease they can tweak them for different variants etc are we looking at a huge step in the advancement of vaccines.

They always say disasters bring about the biggest jumps in technology.
 


Took ‘em a while but they got there in the end. Seems strange to not give both doses though. Where’s the evidence of one dose efficacy?


I agree its a unusual, we've got form though in going against the grain, previously with dosing interval and now this.

I don't think there is much to be honest on the efficacy front truthfully. There is some in adults I think with one-dose VE. The 12-17 adolescent NEJM study I remember looking into efficacy and safety specifically used 7 day post 2nd dose as the end point

There is something regarding myocarditis rates per million much higher post 2nd dose compared to 1st regarding the safety issue
https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.121.056135

Its been a hot issue here since JCVI published their lack of recommendation for the 12-17s, gleefully lapped up of course by the vaccine hesitants and outrage from the long covid types (Gurdasani, Prof Pagel etc)

I've seen a few paeds doctors in the states who seem credible I think disagree regarding some of the extrapolations of current studies JCVI are using/general concerns from myocarditis post-vaccine POV


Children being able to consent for themselves without parental involvement for this in schools another hot button issue here too, expecting a bit more backlash to this than before once talkradio, LBC and GB news get into gear.
 


Took ‘em a while but they got there in the end. Seems strange to not give both doses though. Where’s the evidence of one dose efficacy?

The tests they're looking at are against hospitalisations/deaths.

https://assets.publishing.service.g...465/Vaccine_surveillance_report_-_week_36.pdf are calculating:
For delta - Single dose - 80% (69 to 88)
The antibody studies suggest the vaccines kick in fast in the under 30s so it's a reasonable compromise to keep schools functioning well during autumn term while they wait for more data. Whether it does that is the watch this space element of the story.

The myocarditis risk in young teenagers seems to be heavily weighted towards the second dose.
 
The tests they're looking at are against hospitalisations/deaths.

https://assets.publishing.service.g...465/Vaccine_surveillance_report_-_week_36.pdf are calculating:
For delta - Single dose - 80% (69 to 88)
The antibody studies suggest the vaccines kick in fast in the under 30s so it's a reasonable compromise to keep schools functioning well during autumn term while they wait for more data. Whether it does that is the watch this space element of the story.

The myocarditis risk in young teenagers seems to be heavily weighted towards the second dose.

It just seems like a(nother) fudge. If you conclude the risk:benefit is positive (taking into account societal benefits etc) then go with the dosing regime used in the licensing studies. That’s the most robust demonstration of benefit we have. Underdosing could end up reducing benefit at the expense of trying to reduce risk. So the ratio of risk:benefit doesn’t actually improve.
 
It just seems like a(nother) fudge. If you conclude the risk:benefit is positive (taking into account societal benefits etc) then go with the dosing regime used in the licensing studies. That’s the most robust demonstration of benefit we have. Underdosing could end up reducing benefit at the expense of trying to reduce risk. So the ratio of risk:benefit doesn’t actually improve.




Dr June Raine chief exec of MHRA said that there is "evidence that the vaccine provides protection before dose two" about 18 mins in but not elaborated on much
Whitty said decision mainly predicated on reducing education disruption and also done in conjunction with the royal colleges. They want to avoid stigmatisation and very much gave the advice that this is more of a grey area i.e. marginally benefit in vaccinating 12-15 who are healthy

Comments bizarrely a cesspool, usually dont associate guardian with the antivaxx but I think they're coalescing around anything related to Chris Whitty and seething at this decision. I fear for his safety.
 
It just seems like a(nother) fudge. If you conclude the risk:benefit is positive (taking into account societal benefits etc) then go with the dosing regime used in the licensing studies. That’s the most robust demonstration of benefit we have. Underdosing could end up reducing benefit at the expense of trying to reduce risk. So the ratio of risk:benefit doesn’t actually improve.
Beyond my pay grade really. I'm seeing paediatricians and cardiologists scrap it out on Twitter over the data that has/hasn't been released by the regulators. EMA and the CDC aren't seeing quite the same thing at the moment.

At any rate, this is what the data aggregated by MHRA/JCVI looks like. It's pretty clear why they want to pause after dose 1. They're also looking at why some people are affected and not others, which might lead to advice on exercise for the days after the jab or for more guidance on early symptoms.

 
Beyond my pay grade really. I'm seeing paediatricians and cardiologists scrap it out on Twitter over the data that has/hasn't been released by the regulators. EMA and the CDC aren't seeing quite the same thing at the moment.

At any rate, this is what the data aggregated by MHRA/JCVI looks like. It's pretty clear why they want to pause after dose 1. They're also looking at why some people are affected and not others, which might lead to advice on exercise for the days after the jab or for more guidance on early symptoms.



It’s above my pay grade too. I’ll leave it to the paediatricians and cardiologists to scrap it out. That info graphic makes very little sense though. If we take the “after 1 dose” efficacy seriously then the JCVI should have found in favour of vaccination with their initial review.

Would also love to know where they got their evidence of such marginal gains from a second dose when very early on in the delta pandemic it became obvious that a second dose is crucial for adequate protection.

Anyhoo. I’m glad my kid got both doses. He was grand after dose 1 but got a solid 24 hour febrile illness after dose 2. To me that was evidence of robust activation of his immune system. So was good to see.
 
It’s above my pay grade too. I’ll leave it to the paediatricians and cardiologists to scrap it out. That info graphic makes very little sense though. If we take the “after 1 dose” efficacy seriously then the JCVI should have found in favour of vaccination with their initial review.

Would also love to know where they got their evidence of such marginal gains from a second dose when very early on in the delta pandemic it became obvious that a second dose is crucial for adequate protection.

Anyhoo. I’m glad my kid got both doses. He was grand after dose 1 but got a solid 24 hour febrile illness after dose 2. To me that was evidence of robust activation of his immune system. So was good to see.
Timing of second doses has always been a bone of contention between JCVI and the rest of the world. :smirk:

They believe the low risk of serious covid in under 16s more or less vanishes once you double vax the known clinically vulnerable - which they already supported. What data they do have suggests that if you're young and not immune suppressed, dose 1 has a massive impact on the likelihood of covid causing a serious illness. The antibody studies back them up on that as well.

They want more dose 2 data from Europe and more recovery/follow-up data from the US. They also believe that if the data demands - they can switch on the second dose rollout soon after, the luxury of having vaccines available if they want them.

It might look like a fudge, but it's a fudge that buys them time, and benefits the kids.