What do you make of this statement by Merck the makers of Ivermectin?
https://www.merck.com/news/merck-statement-on-ivermectin-use-during-the-covid-19-pandemic/
Sorry I've been busy. I wanted to find more of the studies I've seen cited. Found one that's a preprint and that's also being questioned. Are there usually so many questioned studies? Is there some kind of conspiracy to make ivermectin look effective? Could be.Why am I not surprised that @Beans has not replied to above.
Sorry I've been busy. I wanted to find more of the studies I've seen cited. Found one that's a preprint and that's also being questioned. Are there usually so many questioned studies? Is there some kind of conspiracy to make ivermectin look effective? Could be.
I'm not saying I know the answers, and if all the stuff I've seen had been discredited, and that discrediting stands up over time, I'll happilly accept it all.
If I can get myself to do it I'll look for more of the data I've seen.
But yes, Merck say it doesn't work, right? Maybe they're right!
Yep. 62% of the adult population have had at least one dose, and around 57% have had a full course (that's about half of the whole population of the state). A tragedy in a country where vaccines have been freely available for months.Only 57%?
Is a medicine that's been used by humans for a while, it's a good one, and finding new purposes for old medicines is, as we say in the States, a thing.Not to mention why would it be a surprise that a horse dewormer wasn't a cure for covid?
Is a medicine that's been used by humans for a while, it's a good one, and finding new purposes for old medicines is, as we say in the States, a thing.
Not 100% sure but I think not. Wasn't anti vaxx or anything.
He has passed away since I initially posted. His wife had given birth to a son whilst he was in a coma. Gutted as he was such a nice and humble guy.
Regarding the vaccine, AZ in particular, there is a radio personality who died after having it. I mentioned another guy who has had a stroke and blood clots and my own mother passed away 6 months ago from stroke after the AZ jab.
A summary of bad news from Covax. Covax are supposed to be the main source of vaccines for whole chunks of the world. They're now expecting to receive only limited supplies in 2021.
Part of the story is vaccine hoarding by the rich (including stock that is having to be destroyed as it's reached its use by date). Which has now turned into another round of stockpiling in case boosters are needed.
The other issues mostly relate to the difficulty of scaling up production. Pfizer has been the only company that actually managed to scale up, more or less on plan.
Sorry I've been busy. I wanted to find more of the studies I've seen cited. Found one that's a preprint and that's also being questioned. Are there usually so many questioned studies? Is there some kind of conspiracy to make ivermectin look effective? Could be.
I'm not saying I know the answers, and if all the stuff I've seen had been discredited, and that discrediting stands up over time, I'll happilly accept it all.
If I can get myself to do it I'll look for more of the data I've seen.
But yes, Merck say it doesn't work, right? Maybe they're right!
Study done only in the US. But interesting when considering vaccine for teenagers.
Boys more at risk from Pfizer jab side-effect than Covid, suggests study
US researchers say teenagers are more likely to get vaccine-related myocarditis than end up in hospital with Covid
https://www.theguardian.com/world/2...zer-jab-side-effect-than-covid-suggests-study
Study done only in the US. But interesting when considering vaccine for teenagers.
Boys more at risk from Pfizer jab side-effect than Covid, suggests study
US researchers say teenagers are more likely to get vaccine-related myocarditis than end up in hospital with Covid
https://www.theguardian.com/world/2...zer-jab-side-effect-than-covid-suggests-study
Had my second does of moderna yesterday, last time had no side effects just a sore arm. After I had the jab yesterday I was fine for most of the day but during the night I had shivers/high temp and couldn't sleep. Hopefully means the vaccine is working effectively.
Good to hear that mate.Had mine Tuesday evening, felt pretty terrible by Wednesday lunchtime. Headache, dizziness, shivers and a general “fluey” feeling. It passed quite quickly though, by Thursday I felt ok again.
This is the inactivated virus vaccine that was going to be made in Livingstone.
I'm not sure if this is about timescales being pushed back, or if something has gone wrong with that factory project. Either way, not great news for Valneva who had been looking at modifying their vaccine to target variants. The vaccine is at phase 3 trials right now.
I think this is the trial that @lynchie was on - not sure if he still is.
Took ‘em a while but they got there in the end. Seems strange to not give both doses though. Where’s the evidence of one dose efficacy?
Took ‘em a while but they got there in the end. Seems strange to not give both doses though. Where’s the evidence of one dose efficacy?
The tests they're looking at are against hospitalisations/deaths.
https://assets.publishing.service.g...465/Vaccine_surveillance_report_-_week_36.pdf are calculating:
For delta - Single dose - 80% (69 to 88)
The antibody studies suggest the vaccines kick in fast in the under 30s so it's a reasonable compromise to keep schools functioning well during autumn term while they wait for more data. Whether it does that is the watch this space element of the story.
The myocarditis risk in young teenagers seems to be heavily weighted towards the second dose.
It just seems like a(nother) fudge. If you conclude the risk:benefit is positive (taking into account societal benefits etc) then go with the dosing regime used in the licensing studies. That’s the most robust demonstration of benefit we have. Underdosing could end up reducing benefit at the expense of trying to reduce risk. So the ratio of risk:benefit doesn’t actually improve.
Beyond my pay grade really. I'm seeing paediatricians and cardiologists scrap it out on Twitter over the data that has/hasn't been released by the regulators. EMA and the CDC aren't seeing quite the same thing at the moment.It just seems like a(nother) fudge. If you conclude the risk:benefit is positive (taking into account societal benefits etc) then go with the dosing regime used in the licensing studies. That’s the most robust demonstration of benefit we have. Underdosing could end up reducing benefit at the expense of trying to reduce risk. So the ratio of risk:benefit doesn’t actually improve.
Beyond my pay grade really. I'm seeing paediatricians and cardiologists scrap it out on Twitter over the data that has/hasn't been released by the regulators. EMA and the CDC aren't seeing quite the same thing at the moment.
At any rate, this is what the data aggregated by MHRA/JCVI looks like. It's pretty clear why they want to pause after dose 1. They're also looking at why some people are affected and not others, which might lead to advice on exercise for the days after the jab or for more guidance on early symptoms.
Timing of second doses has always been a bone of contention between JCVI and the rest of the world.It’s above my pay grade too. I’ll leave it to the paediatricians and cardiologists to scrap it out. That info graphic makes very little sense though. If we take the “after 1 dose” efficacy seriously then the JCVI should have found in favour of vaccination with their initial review.
Would also love to know where they got their evidence of such marginal gains from a second dose when very early on in the delta pandemic it became obvious that a second dose is crucial for adequate protection.
Anyhoo. I’m glad my kid got both doses. He was grand after dose 1 but got a solid 24 hour febrile illness after dose 2. To me that was evidence of robust activation of his immune system. So was good to see.