The vaccines | vaxxed boosted unvaxxed? New poll

[Ødegaard]

You must have had a million million blood samples though Ody, strange it's not been detected before. Good luck with it anyway.

Most likely has come due to being overweight. My mother, grandmother and great grandmother had type 2, so I'm hoping for just a change in diet and a pill or two more. I won't notice that much.

Was found in 2 random bloodsamples last 30 ish days. Last one was a few days ago and I had values of 70 for longterm bloodsugar and 15 for short term.
If I remember correctly they should be on below 40 and 8 respectively.

I have had normal samples until now.

 

[ThatsGreat]

I’d rather see the data on that from a legit source.

Covaxin if you have the choice is the one to go for. I chose covidshield(AZ) over it due to prejudice against Indian developed products and had a mild fever for a couple of days after the vaccination. Covaxin guys suffered no reaction and it's said to be as affective as covidshield.

 

[Wibble]

A weird side effect of our governments feck up with betting the bank on AZ and a failed UQ vaccine is that I'll be able to get vaccinted with AZ in a couple of weeks now as they are now allowing all over 50's to get it because we have lots. What little Pfiser we have is being kept for the U50's.

 

[jojojo]

I think Hungary got some, a friend of mine over there are saying her parents refuse to take that or the Chinese one

Sputnik has some decent evidence on its side. It just doesn't yet have the kind of high volume (millions of doses - with published adverse reaction data) evidence that some of the others have.

The Chinese ones, I'm more suspicious of - though there are multiple vaccines and multiple manufacturers. In general with those it comes down to lack of solid published trials evidence and some wildly disparate trial methodologies and results where they have been revealed. The inactivated virus ones in particular seem to have low efficacy, and the inactivation process doesn't have published results.

 

[golden_blunder]

Some bad news too, found out from bloodsamples that I am diabetic.
Gonna go check that out in 20-30 minutes.


So far today only a sore arm again, so it seems like I will be fine from the vaccine.

Good luck with that. Just remember if it’s type2 you can affect it in a positive way too

 

[golden_blunder]

Sputnik has some decent evidence on its side. It just doesn't yet have the kind of high volume (millions of doses - with published adverse reaction data) evidence that some of the others have.

The Chinese ones, I'm more suspicious of - though there are multiple vaccines and multiple manufacturers. In general with those it comes down to lack of solid published trials evidence and some wildly disparate trial methodologies and results where they have been revealed. The inactivated virus ones in particular seem to have low efficacy, and the inactivation process doesn't have published results.

Yeah regarding Sputnik I’d want to see the evidence

regarding the Chinese ones didn’t the head guy come out last week saying it was 51% efficacy?

 

[Pogue Mahone]

J&J data published in The Lancet. Looks good.

 

[11101]

Sputnik has some decent evidence on its side. It just doesn't yet have the kind of high volume (millions of doses - with published adverse reaction data) evidence that some of the others have.

The Chinese ones, I'm more suspicious of - though there are multiple vaccines and multiple manufacturers. In general with those it comes down to lack of solid published trials evidence and some wildly disparate trial methodologies and results where they have been revealed. The inactivated virus ones in particular seem to have low efficacy, and the inactivation process doesn't have published results.

There are increasingly credible rumours that Sputnik might get EMA approval in future. More and more individual countries are talking about ordering it.

Isn't the Sinovac vaccine the main one on offer in the handful of countries like Chile where vaccination isn't working?

 

[evil_geko]

Pfizer, 24 hours later, aside from annoying arm ache so I couldn't sleep on that side, all good for now.

I read that Pfizer, even though not as efficient, does a pretty good job against the newest SA strain?

 

[Traub]

J&J data published in The Lancet. Looks good.

Overall positive.

Does anyone know the difference between the severity categories: mild vs. moderate vs. severe? When you read the paper, hospitalisation and death is not considered severe (i.e. worse), whereas I thought that's what severe would represent. Thought this was some good info:

In South Africa, no hospitalizations of participants with an onset of Covid-19 at least 28 days after administration occurred in the vaccine group, as compared with 6 hospitalizations in the placebo group. All five Covid-19–related deaths in the trial occurred in the placebo group in South Africa.

Pfizer, 24 hours later, aside from annoying arm ache so I couldn't sleep on that side, all good for now.

I read that Pfizer, even though not as efficient, does a pretty good job against the newest SA strain?

That's the thinking, we are only rolling out Pfizer and J&J here in SA.

 

[Pogue Mahone]

Overall positive.

Does anyone know the difference between the severity categories: mild vs. moderate vs. severe? When you read the paper, hospitalisation and death is not considered severe (i.e. worse), whereas I thought that's what severe would represent. Thought this was some good info:

Definitions of mild/moderate/severe are explained in page 19 of the appendix.

Moderate illness seems to be actually fairly mild and mild very close to asymptomatic. Severe/critical cases are sick as feck though.

 

[BD]

What's the story with medicine for side effects after the Pfizer vaccine? Have read two sources so far and naturally enough, one said paracetamol and not ibuprofen, while the other said ibuprofen but not paracetamol.

 

[Traub]

Definitions of mild/moderate/severe are explained in page 19 of the appendix.

Moderate illness seems to be actually fairly mild and mild very close to asymptomatic. Severe/critical cases are sick as feck though.

Thanks. Severe looks bad. I'd imagine most of the cases relate to oxygen saturation below 93% or fast heart rate (both of which could be managed at home), given the others would likely result in hospitalisation, and there weren't any cases of this > 28 days.

 

[evil_geko]

Overall positive.

Does anyone know the difference between the severity categories: mild vs. moderate vs. severe? When you read the paper, hospitalisation and death is not considered severe (i.e. worse), whereas I thought that's what severe would represent. Thought this was some good info:



That's the thinking, we are only rolling out Pfizer and J&J here in SA.

Yeah, that was what I read the other day.

 

[Pogue Mahone]

What's the story with medicine for side effects after the Pfizer vaccine? Have read two sources so far and naturally enough, one said paracetamol and not ibuprofen, while the other said ibuprofen but not paracetamol.

Either would be fine.

Although my preferred prescription for a transient fever/sore arm would usually be the following.

Spoiler: Rx

 

[BD]

Either would be fine.

Although my preferred prescription for a transient fever/sore arm would usually be the following.

Spoiler: Rx

I just wanna feel sorry for myself for a few days, and taking medicine helps add to that feeling. I'd be in calpol if I could get it here.

 

[Pogue Mahone]

I just wanna feel sorry for myself for a few days, and taking medicine helps add to that feeling. I'd be in calpol if I could get it here.

I find a high fever weirdly enjoyable. Curl up in bed with Netflix on the iPad and relish the sickness!

 

[BD]

I find a high fever weirdly enjoyable. Curl up in bed with Netflix on the iPad and relish the sickness!

To be fair I've been very lucky and have never had more than some sniffles, but the way I react to a hangover makes me dread how bad I'll take a fever or proper flu symptoms.

 

[Bosws87]

I find a high fever weirdly enjoyable. Curl up in bed with Netflix on the iPad and relish the sickness!

Right...

 

[prateik]

J&J data published in The Lancet. Looks good.

As someone who has no idea how to interpret these numbers, is 85% against severe/critical good? Most covid cases arent severe/critical..

Or does it mean the vaccine significantly reduces the change of a person getting infected.. and of that tiny portion, it guards against severe cases at that rate (85%) ..

 

[Pogue Mahone]

As someone who has no idea how to interpret these numbers, is 85% against severe/critical good? Most covid cases arent severe/critical..

Or does it mean the vaccine significantly reduces the change of a person getting infected.. and of that tiny portion, it guards against severe cases at that rate (85%) ..

It means there’s an 85% reduction in severe/critical cases when you compare the number in the study arm that got vaccinated vs the placebo arm.

There’s a 75% reduction in cases of any severity, from 28 days after the jab (the numbers being compared here include all cases, which includes critical/severe as well as mild/moderate(

I’d say the second figure is the more compelling of the two.

The equivalent stats for Pfizer/Moderna are much more impressive but they were tested at a time when the dominant variant was a lot less infectious and caused less severe illness.

We also need to remember that compared to the efficacy of viral vaccines in general (especially influenza) these results are all pretty spectacular.

 

[jojojo]

As someone who has no idea how to interpret these numbers, is 85% against severe/critical good? Most covid cases arent severe/critical..

Or does it mean the vaccine significantly reduces the change of a person getting infected.. and of that tiny portion, it guards against severe cases at that rate (85%) ..

It's probably easier to visualise from the raw numbers:
They had 432 moderate or severe cases in the placebo group v 193 in the vaccinated.
They had 78 severe/critical cases in the placebo group v 21 uncaccinated.

They had deaths in the placebo group and none in the vaccinated.

In other words, it makes you less likely to have significant symptoms, your odds look even better if you only look at severe cases, and they look better again if you think about deaths. Basically it's dialed the whole virus back a couple of notches.

 

[prateik]

It means there’s an 85% reduction in severe/critical cases when you compare the number in the study arm that got vaccinated vs the placebo arm.
...

It's probably easier to visualise from the raw numbers:
They had 432 moderate or severe cases in the placebo group v 193 in the vaccinated.
They had 78 severe/critical cases in the placebo group v 21 uncaccinated.

They had deaths in the placebo group and none in the vaccinated.
..

Thanks a lot..
looked at the table from the article ... should have done it earlier..

Spoiler

 

[Grinner]

I find a high fever weirdly enjoyable. Curl up in bed with Netflix on the iPad and relish the sickness!

Can you recommend an illness that will see me incapacitated for a week or more, sweating profusely, no appetite but no long-lasting effects? I'd like a little kick-start on weight-loss but don't have the discipline to exercise and diet. Covid gets results but I'm worried about long covid and lung damage.

 

[Pogue Mahone]

Thanks a lot..
looked at the table from the article ... should have done it earlier..

Spoiler

Most pleasing thing about that table is very similar results to the US in South Africa and Brazil.

I need to read the whole article. Did they present results for mild cases?

 

[Pogue Mahone]

Can you recommend an illness that will see me incapacitated for a week or more, sweating profusely, no appetite but no long-lasting effects? I'd like a little kick-start on weight-loss but don't have the discipline to exercise and diet. Covid gets results but I'm worried about long covid and lung damage.

Tough one. We seem to have basically wiped out flu for the moment, which reduces your options. Maybe a good dose of food poisoning? A feed of rotten mussels should do it.

 

[Grinner]

Tough one. We seem to have basically wiped out flu for the moment, which reduces your options. Maybe a good dose of food poisoning? A feed of rotten mussels should do it.

I don't fancy stomach cramps and three days of shits. Like you said, a fever is quite doable and a bit of chicken soup is all you need.

 

[jojojo]

I don't fancy stomach cramps and three days of shits. Like you said, a fever is quite doable and a bit of chicken soup is all you need.

You might want to consider summer vomiting disease. Symptoms not great but a real kick start to any diet.

 

[golden_blunder]

You might want to consider summer vomiting disease. Symptoms not great but a real kick start to any diet.

The good old Norovirus should do it

 

[Rektsanwalt]

Can you recommend an illness that will see me incapacitated for a week or more, sweating profusely, no appetite but no long-lasting effects? I'd like a little kick-start on weight-loss but don't have the discipline to exercise and diet. Covid gets results but I'm worried about long covid and lung damage.

methamphetamines should do as well

 

[prateik]

Most pleasing thing about that table is very similar results to the US in South Africa and Brazil.

I need to read the whole article. Did they present results for mild cases?

Don't think they had any data for that.. 1/3 cases for the 2 groups..
it does say

A preliminary analysis indicated that Ad26.COV2.S provided at least 66% protection against serologically confirmed asymptomatic infection with SARS-CoV-2.

 

[R'hllor]

Is there any country administering Sputnik V?

India has that available from next month.. wondering if that's a good option compared to AstraZeneca

Serbia having a option to choose Sputnik V, can share info i got when i was enlisting my parents, at the time got told that due their age 65+ and health issues they have it wasnt recommended for them to take it, few weeks after i heard that recommendation changed a bit for others interested in it.

Edit: When it comes to Chinese vaccine, there are two different ones, Sinovac and Sinopharm, one should be private and other state production.

 

[Skills]

Got my first Pfizer jab a few hours ago. Honestly haven't felt a thing so far, so fingers cross that's how it stays

 

[Water Melon]

Serbia having a option to choose Sputnik V, can share info i got when i was enlisting my parents, at the time got told that due their age 65+ and health issues they have it wasnt recommended for them to take it, few weeks after i heard that recommendation changed a bit for others interested in it.

Edit: When it comes to Chinese vaccine, there are two different ones, Sinovac and Sinopharm, one should be private and other state production.

A very close friend of mine works as a nurse in one of Moscow clinics. They are now having hospitalizations of people who had their Sputnik shots. However, they are not allowed to record Covid in their health records. Thus, Sputnik seems to be as reliable as Chinese vaccines. 5/10 Would not take unless no other vaccine is on tne horizon in the next 12 months.

 

[Pogue Mahone]

 

[zing]

This thread is outstanding.

For the science types on here -- these findings seem consistent with the AZ findings.. can we expect the probabilities to converge for the two vaccines once more data is available? Is the underlying cause expected to be exactly the same?

This presentation seems to be more certain in their statement that the issue is more prevalent in women - something the EMA avoided saying. It does seem to be based on limited data.

 

[massi83]

This thread is outstanding.

For the science types on here -- these findings seem consistent with the AZ findings.. can we expect the probabilities to converge for the two vaccines once more data is available? Is the underlying cause expected to be exactly the same?

This presentation seems to be more certain in their statement that the issue is more prevalent in women - something the EMA avoided saying. It does seem to be based on limited data.

Good stuff. Even more detailed than an AZ press release! Seems like they will continue with it, as they should.

 

[massi83]

Good stuff. Even more detailed than an AZ press release! Seems like they will continue with it, as they should.

And they indeed did recommend the continuation of usage for everyone over 18. Voting was: 10 in favor - 4 opposed - 1 abstention. The other main option was that it would be banned from women under 50. But they thought it would be confusing and that it would increase vaccine-hesitancy.

 

[Wibble]

This thread is outstanding.

For the science types on here -- these findings seem consistent with the AZ findings.. can we expect the probabilities to converge for the two vaccines once more data is available? Is the underlying cause expected to be exactly the same?

This presentation seems to be more certain in their statement that the issue is more prevalent in women - something the EMA avoided saying. It does seem to be based on limited data.

Probably too early to tell but common factors seem to be that adenovirus based vaccines seem to be affected but that it is very rare and affects younger women the most (although youngerv women who are nurses/doctors/health professionals were a large proportion of the initial vaccination program so it maybe mainly proportional). I also suspect that now we are looking for it the fatality rare will reduce.

Adenoviruses affecting platelets is thought to be the first step and an additive to AZ is thought to be the second factor that in combination trigger clots. That the J&J vaccine seems to have similar issues but doesn't have the same additive makes this hypothesis less certain to be the whole answer.

https://www.webmd.com/vaccines/covi...sts-find-how-astrazeneca-vaccine-causes-clots

 

[DM07]

Anyone has a detailed insight on what's going in the US with the restrictions regarding patents and is it hampering vaccine manufacturing in other parts of the world?

Also is it true that there are 40 mn AZ doses lying still in the US which they are never going to be using? If that's the case then they should export it to a country like India or the Covax initiative and let those who want to use them vaccinate their own people.