I got my vaccine two weeks ago and I've been a bit unwell in the past 2 days - stomach cramps, diarrhea and a temperature. Probably unrelated I guess.
The vaccines | vaxxed boosted unvaxxed? New poll
- Thread starter Badunk
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Agreed. In three weeks.
True. Also Matt Lucas released “thank you baked potato” which was probably better messaging than the government ones at the time
That happened to me watching Mourinhos United
A colleague of a friend of mine (medical consultant) was pretty sick from covid in April. Became symptomatic 14 days after first dose of Pfizer vaccine. Covid +ve today. So that sucks.
Sheesh - don't ask him to buy your lottery tickets.
Is it likely that most people who had the disease in April-May have now lost any immunity they had gotten?
Dunno about most but some would have. Would like to think they’d respond better than most to a single dose of vaccine though.
On the plus side, the vaccines have been very good at keeping people from becoming critically ill if they do still become positive, haven’t they?
I gathered the main thing from the vaccine was stopping hospitalizations and deaths. You will most likely become sick and probably will shed the virus just the same, we'll have to see it's reduced any. Really just makes you more equipped to not end up in a bad way.
Europe have announced that Pfizer will deliver as normal from next week, and will increase planned deliveries from mid February. It's just this week that experienced a slight reduction (-29% in Italy). It's hardly the disaster that some countries were trying to make out.
Do we know if the immune response from the vaccines (after 2 shots+ week/best case) is similar, better or worse than what the body would have after an average covid infection ? In terms of longevity / months.
I know the CDC had suggested 3 months as the time frame after which people had tested positive could be infected again.. The new guidelines from the US is anyone entering needs a covid negative test or proof that they recovered from it in the last 3 months....
so they are still using that 3 month as a guideline for policy making.
No we don’t. There are reports out of Israel of much higher levels of antibodies after vaccination than after infection but there isn’t always a direct correlation between antibody levels and immunity and the vaccines haven’t been around long enough to see evidence of efficacy for more than a few months.
Getting my Pfizer vaccine on Tuesday. We have another outbreak at work and one of the staff who tested positive had Covid in the first wave, too. She was also vaccinated a week ago. A few of the staff reported feeling rough and some residents have flu type symptoms.
How sick is she compared to her first bout?
Has just felt fatigued and under the weather. She was in today but was sent home when the test results arrived this afternoon. She had it bad in the first wave, couldn't finish a sentence without stopping for breath.
Music to my ears. It’s looking more and more like immunity is short lived and variable but there does seem to be a trend towards second and subsequent bouts being minor. Which is exactly what you’d hope for. This fecking virus has become so ridiculously contagious that eradication might be off the cards but if a combination of vaccination and repeat infections helps it it become just another flu then that’s all good.
She was also the first to get it, around mid-March. I got it at the end of May. I'm hoping for a wee bit more immunity until the vaccine kicks in
With most highly effective vaccines the response is usually better on average than with natural infections isn't it? I agree we don't have the data for covid yet of course.
I’m not actually sure. The effectiveness of the vaccine tends to correlate with the effectiveness of natural immunity. Hence you only catch measles once and only need to be vaccinated against it once. While you need to be vaccinated against influenza multiple times and can catch it every year. Could be wrong though. Any specific vaccines you’re thinking of?
Actually HPV vaccine works better than infection at giving you immunity. Although I think that’s down to a fairly unique way it evades your immune system, rather than a waning response.
No. I just seem to remember reading that somewhere - could be remembering wrong.
Flu is an odd one though because I think it is the large number of true strains, that each require a re-jigged vaccine component, that is the cause (or main cause) of the relatively low effectiveness. Include the right strains in your vaccine and the effectiveness is great but don't and it is rubbish. Plus the flu evolves quickly.
I also seem to remember that we don't really understand (or fully understand) why some vaccines last for life and others need boosters are varying intervals even when the issues experienced with influenza are absent.
I'd bet that there is going to be a huge surge of interest from students trying to study to get into immunology/virology post-pandemic. And why not? You could literally be saving the world in some cases.
I think that is my favorite vaccine.
At the very least, if my immunology prof from Uni is anything to go by, you could be appearing on Tv/radio on an almost daily basis from start to finish of the next pandemic!
The simple answer is: it varies. Immune system varies significantly among individuals and this includes immune responses. HBV vaccines theoretically provide very long term protection (almost lifetime), but I found my antibody level very low last year and needed a booster dose.
Influenza vaccines, however, are not really an accurate example. The major reason we need them multiple times is that flu virus undergoes drift and shift mutations very rapidly.
https://www.nytimes.com/2020/12/05/health/covid-natural-immunity.html
Science funding is still crap. Short term contracts etc. Already way too many PhDs to postdoc jobs. Much better off studying medicine if you want to do research. Not that I’m bitter haha
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Some things never change. I quit halfway through my PhD because the best offer in my field post qualification was a 1 year contract as an Associate lecturer, which was peanuts at the time and then I'd still have had to find my own research funds or piggy back on my supervisor and associates - which is far from certain funding. Add on to that 20+ weeks away in the field on top of a full teaching load when my son was a toddler and I politely declined and returned my scholarship.
I was informally offered a place in a postgrad medicine degree in my mid 40's but the idea of very little income for the 7+ years or more if you wanted to specialise wasn't attractive at that age.
Nope, because it wasn't planned. Literally until the day before my 2nd dose was due, my trust was still planning on giving it (against the new government guidance) and I think only changed tack due to significant pressure from higher up.
Whether they're collecting a bit more data now on a societal scale, I'm not sure. I've personally not heard anything like that but perhaps scientists are doing that in some parts of the country?
Like you said, we really should, especially if we're going so far off licence.
I also wonder whether the government is opening itself up to legal action in the future here.
City AM: Astrazeneca delays vaccine delivery to EU
And more from the FT here: EU hit by delay to Oxford/AstraZeneca vaccine delivery
And more from the FT here: EU hit by delay to Oxford/AstraZeneca vaccine delivery
I get the sense you really enjoy posting bad news re the EU! Wouldn’t be too worried about this tbh. I remain to be convinced it’s a good vaccine. At the very least we need a better idea how it should be dosed. Hopefully have more data by the time we start injecting.Haha, it's the top story on the FT right now! Honest, guv.
Good! I'd much rather have one of the more effective ones.
It’s weird being picky about vaccines but I will definitely feel a bit of a pang of disappointment when my time comes round if I’m offered the AZ/Oxford jab. Although hopefully there will be better data published between now and then. I’m literally bottom of the queue so plenty of time left for them to convince me it’s as good as the others.
You’d hope this would be easy to get a taxi and claim the expense back on the NHS
i dunno what the plan is around the country but my nan is late 80s and lives miles from town but they came to her house to vaccinate her
Same for mine
They gave her the Oxford one as the pfizer one can't be transported as it needs to be at a certain temp (high?) Whilst Oxford doesn't
You’d expect them to deploy community nurses to do it as they visit lots of old people anyway.
Is there a list of health conditions that mean that you cannot take the Oxford vaccine available somewhere please?