I wouldn't. He's costly, injury prone, will get rotated more than the rest of that team... you're better off keeping Kane than getting Aguero to be honest.
I'm not a fan of the rotation. I like having a bench that will just play and will only come in to fill in for injuries.
I have a deep team so will have to rotate but will try to not rotate my offensive players too much. From now on in my midfield I am going to have Salah, Grealish and Ziyech as permanent fixtures, and rotate Son and Rodriguez when needed, and in my attack Werner and DCL will play, Adams will be based on fixtures. I have to leave out at least 1 of Adams, Son and Rodriguez everytime though. In defence Chilwell will always feature, then it will be two or three from Cresswell, Dias, Bellerin, Vestergaard. Dias will be based on fixtures as he probably won't do much on offense, the others are quite potent offensively though so may be a bit tougher.