When it became apparent that we were going with a 4-2-2-2, I said it could be problematic because, as an interior(10) in the system, you need to be press resistant and Bruno isn't. He's very weak.
I listed the interiores the likes of Wenger and Pellegrini have used, and, like Sancho, they're what we need. Players who can hold the ball under pressure, carry it forwards, produce quick 180/360 turns to leave opponents for dead and get us moving when receiving the ball in half spaces.
Problem is, bar Sancho, we don't really have anyone so, yes, Bruno needs dropping, but for who?
Our other two best options for the interior are Pogba and Martial, and neither are available. In regards to Martial, it probably wouldn't matter if he was available as his heads gone from Manchester.
Donny and Lingard are too weak. Amad and Elanga probably aren't ready. Maybe Greenwood, but you want your interiores to help dictate a game and link the midfield to the attack, and, right now, Greenwood drifts out of games too often so he'd be better suited to one of the CFs who drift wide when the interior cuts in.