I see no evidence it's going to change in the general election. No GOP candidate wins a national general election without turning out that MAGA base. Trump didn't moderate himself in either 2016 or 2020.
I see no indication that any GOP candidate would suddenly drop their anti-woke gameplan just because it's a general election simply because they can't afford the MAGA base staying home. And that base will stay home more than moderate independents might suddenly switch to De Santis suddenly spewing less radical rhetoric in a general election. Between COVID and the SCOTUS disrupting Roe v Wade, they know the only way to win the general election is turning out their base plus voter suppression and de-energizing the Dem base.
The difference is the introduction of independents into the mix, which aren't a consideration during the primaries because candidates are focused on tailoring their message to appeal to the base. They know they can't win a general election with just their base and that most votes come from independents, which means they have to widen the aperture a bit. Not Trump of course, but most that came before him.