For sure. We don’t need those players at all.
——————de Gea————————
Tuanzebe——Lindelof—-Maguire—-Williams
———McTominay—-Fred—————
Pereira———Pogba————James
——————-Greenwood————-
We will also have a decent bench of Romero, Rashford (may be used instead of Pereira on the right, even as a starter - just not as a CF), Gomes, Garner, Rojo, Mata (sometimes may be useful as a substitute - but never as a starter). One last spot on the bench is up for grabs (Jones for numbers, Chong for numbers, or some of the youngsters). Gomes is also injures? Ok, put Hannibal or Levytt there on the bench.
Then again all the above is for the situation when Martial, AWB and Shaw are injured. Add those three in and there are no problems whatsoever actually.