Not really. With two up top, I can imagine Van Gaal will always want one of his strikers dropping off and linking up with the midfielders, with the other one playing on the last man. It also means, players can make runs in behind.
In the first half, Rooney did a lot of the dropping off, while Van Persie was playing on the last man. When Rooney went in behind the forwards, Van Persie did a lot of the dropping off, while Falcao played on the last man.
I think variation in attack and unpredictability is a pain for the opposition, and it showed today.