Walker, Rose (clearly wanted out but was unable to find a suitor), Eriksen, Vertonghen, Alderweireld are hardly the worse players in the squad. They are or were the back bone of the fist team.
Walker, despite romantic memories, has and always was a liability. He still makes errors for City. He'd been replaced by Trippier by about half way though the season for that purpose. Regardless, that was a fair few seasons ago so it's a grasp.
Rose has not been good for quite a long time - he has spend most of the last couple of seasons struggling or injured, so it's comical to suggest he's one of the best players - this is further evidenced by the fact that no one wants him despite the club making him publicly available. Watford were the only ones linked on TDD, and they seemingly pulled out.
Eriksen has been disinterested for around a year now, and has been hitting the first man in free-kicks and corners for several seasons now. Considering that was his 'speciality', it's pretty poor from him. Again, no one wanted him when he was available, and he is most definitely no where near the best player in the squad and hasn't been for some time.
Alderweireld was available for buttons (comparatively) in the summer, and has consistently claimed he is happy and doesn't want to leave. Again, no one wanted him. He was solid a few seasons ago, but has also been very poor in recent times. Davinson Sanchez was brought in as his replacement a few seasons back due to this anticipation.
Vertonghen has also publicly claimed he wants to stay (
https://www.theguardian.com/football/2019/sep/30/ambitious-jan-vertonghen-extend-time-tottenham) , but will be 33 in April. Age is showing and he's far from one of the best players at the club, and very few clubs would be extending the contract of an ageing off-form defender in any hurry.
Not sure what the "fist" team is, but those players aren't the back bone. If you want to break down the better players in the squad, there are no others who claim to want to leave except for Aurier, who is turd anyway. All the others seem to be perfectly happy and are on long term contracts.
So, to put it succinctly, the only players who are close to leaving are the ones that the club want to get rid of. I'd include Eriksen in that, as he's been nominated as one of the players Pochettino no longer wants (
https://metro.co.uk/2019/09/26/maur...ksen-still-spurs-summer-speculation-10812336/)
Any squad will reach issues with ageing players and moving them on - Utd fans should know this better than anyone. At some point, whether it's with Pochettino or not, Lloris will need replacing (especially due to how his elbow issue might affect his already erratic decline). We probably need another RB and CB. Plenty of other players have already been covered or replaced with the signings of Ndombele, Lo Celso and Sessegnon - one of which has yet to feature, and another barely due to injuries. I'm sure a whole host of other clubs would still bite their hands off for the majority of the players available.