Already doing a dynasty league, just had our first rookie draft after our first season finished. Love it though. So many more dimensions to it in terms of trading for future picks, selling older short term assets for multiple first rounders, etc. Especially close to the draft, everyone will want to start having a piece of a high pick rookie, so theyll start spending loads for a high pick even if they didn't value it before. Having a bad draft really isn't a death sentence because if you finish last, you get 1.01 and then suddenly you can draft a Baker Mayfield or Saquon Barkley (depending on needs) and have a great team all of a sudden.
We do a superflex league, 3 normal flex, 1 SF, 1 QB, 2 WR, 2 RB, 1 TE, no defence/kickers because that's pretty dumb for dynasty IMO. Basically a 2 qb league just added flexibility if you dont have a competent 2nd QB but stacked otherwise. Helps having 2 startable QBs though.
Definitely recommend, though only interested in doing the one. 2 would be overkill.
My 3 rookies were A.J. Brown, Deebo Samuel and Daniel Jones with my last pick for the memes.