Brugge has a few injuries and will be without a few key players . Dennis, forward that made us a lot of problems in the first game is out as well as a captain Vormer.
There are a few important games in the league that is far away from over with just 3 points behind Chelsea, possible City penalty and even Leicester in downtrend. So, with Everton away in a few days I would certainly rest a few.
I guess we can play this one without Maguire and Shaw in the defense, with Williams and Bailly for example. Although I guess Maguire would not be under pressure, I would love to rest him in one game. With WIlliams replacing Shaw I certainly don't have any problem at all.
I would love to rest Matic as well, I guess we don't need that much cover for the defenders and Fred can cover it, while McT can help in the second half and gain match fitness. I wouldn't mind having Garner on the bench to have a run out if everything goes well.
Pereira and Lingard in the starting line up? I wouldn't mind one of them, Pereira probably before Lingard as he can help Fred while also having some space with Bruno upfront.
So, something like:
Romero,
Dalot, Bailly, Lindelof, Williams
Fred, Pereira,
Mata, Bruno,
Martial, Ighalo
I would risk Martial hoping for 2 goals in the first half and would replace him as soon as we are 2 up with Greenwood for example. Also I guess we will be able to pressure them in the final third, and Mata can be crucial to get ball to Bruno or two upfront, while won't need speed to track back. Pereira and Fred can cover, and Bailly is fast enough to recover if needed.
It is risky, but I am pretty confindent in this one. Bench would be like: De Gea, AWB, Maguire, Garner, McTominay, Lingard, Greenwood