Yeah really not sure what to go for here. Definitely need the 3 man midfield, but we need to press and go on the offensive and take the game to them. Also in these games where we'll be under pressure, we need an out ball and someone who can stretch them and run in behind and dribble past players (Rashford or Martial or both). To get one of them and Sanchez in, means one of the 2 play on the right (unless we go for the Chelsea lineup where we used a front 2 and Sanchez as the 10... probably that).
They'll likely rest players, but they're still very good at controlling games, and we normally aren't great at the Etihad, so it'll be tough (especially with Mourinho being away to a big team). Going for:
De Gea
Valencia Bailly Smalling Young
Herrera Matic Pogba
Sanchez
Martial Lukaku