CB: Varane
CM: Fred
LAM: Di Maria
ST: Martial
Other players, I'd like :
13-16 Antonio Valencia
15-22 Luke Shaw
14-18 Chris Smalling
13-18 DDG
17-19 Rashford (the fast dynamic version, not necessarily the most productive version we had)
---------------------- De Gea
-----Smalling --- Varane ----- Martinez
--Valencia ------Ugarte --- Fred ------- Shaw
----------------Di Maria ------- Rashford
--------------------------Martial
Fred + Ugarte give you the legs you need in the middle of the pitch to press and harass teams through the middle. We've had better midfielders than Fred and Ugarte (Pogba, Bruno, Matic & Casemiro for 6 months, Herrera arguably) but I value high energy and pressing in the midfield two more than anything else for this set up. Kante for example was vital for Chelsea's teams that won the title under Conte and then the CL under Tuchel.
Martial, Rashford and Di Maria give you pace to break on teams. Bruno at his best was arguably our best attacker post 2013 but I value pace more.
Ideally I'd want a faster CB than Martinez for the LCB channel but a left footer is also important. There's a case to put Shaw there but there isn't a better LWB option, and Di Maria would be too vital to drop from the forward positions.
Smalling & Varane are probably the most comfortable defenders we've had defending against pace and both were very good in the air. That's important in this set up, especially with Martinez at LCB.