Falcao and Van Persie: does it work? I would argue that the two of them don't work together as a front two, and are both players that should be spear-heading an attack as lone strikers. Falcao is working his way back to fitness after long time out from injury, and I think his goal today is going to be a great confidence boost for him. Van Persie still looks like he's feeling the effects of playing the World Cup, but it's the same World Cup that all these other Dutch players, and Brazilian, German,and Argentinian players played just as much of a part in (if not more), and they don't seem to be struggling.
Removing one of them from the strikeforce to start matches means two things: 1) you've got an experienced striker who can come off the bench if need be, and 2) you can replace them with a midfielder, which helps to solve the issue of losing possession, which is something that Van Gaal knows is an issue because he's spoken about it himself. Taking one of them out doesn't mean that they're relegated to the status of super-sub, because you can always rotate them, and with both of them not quite fit it means that they can get some rest.