According to PhysioRoom, we have RVP and Vidic out, but
Smalling, Evans, Ferdinand, Valencia & Nani are all due back.
On that basis, it give's us more options, I think it's safe to say we play our best stuff with one up top but I feel that 1 can't be Rooney as we need him further back with City's strong midfield, with that in mind I'd go for something like:
DDG
Rafael Smalling Jones Buttner
Carrick Fellaini
Nani Rooney Mata
Welbeck
Subs: Lindegaard, Evans, Fletcher, Kagawa, Januzaj and Hernandez