They're a different calibre in terms of touch/technique/footballing IQ and I wouldn't include Ozil as a typical example as he was used in a more attacking set up by Jose's standards.
What is common across all those players is 10/10 first touch, you'll never see those guys lose control of the ball and their decision making on the ball is top notch.. both short passes, long passes, through balls.
Mkhitaryan is quicker than all of them, but is brainless in comparison and very inconsistent in passing/technique.
This means in a counter-attacking set up, he can (with space) drive into if very effectively and grab goals) but when space is at a premium and the game is tight, high pressured.. he falls to pieces and looks bang average.
Yesterday was an awful performance and after yesterday I don't see him as anything but a squad player going forwards if we want to win the title or challenge for champions league. He is a talented footballer, but he's too flaky and his bottom level technically is poor. At his best, he's a genius, but at his worst.. he's terrible and for a team which is defensive.. we can't afford passengers up front, we need guys who are bang on it 9 times out of 10 and can make the most out of little possession.
In a team which dominates possession and in a free flowing team, he'd be fine I reckon but he's not the ideal link between midfield and attack we need. I can see him becoming a more support type player next year and possibly blossoming in such a role or being phased out altogether if he can't up his game.