Not with the current wingers, in my opinion.
Kane's best attribute, other than his finishing, of course, is his ability to pick a pass. Therefore, he needs runners. If you look at City's current wingers, whilst they do somtimes run in behind, they are not the type to constantly stretch defences like Son, Salah, Rashford, Sterling, etc.
Kane, in my opinion, would have been more suited to City when they lined up with Sterling and Sane on the wings a few years back.
This is why I believe Sothgate should play Rashford/Sterling and Saka either side of Kane during the world cup.