Considerably more high profile, and there is a route to the CEO job down the line.
What it will boil down to is wether or not VDS believes he has achieved what he can with Ajax. Ajax has established themselves as a high performing feeder club to bigger european clubs. The dutch league is not one of the major European leagues. Ajax has of course always been a club that fosters talents, but combining that with success in Europe, AND repeating the same after rebuilding following mass player sales, is a completely different thing.
MUFC is one of the most high profile clubs on the planet, that is trying their best to become one of the best again. Whoever spearheads that operation gets the one of the biggest gold marks on their resume in sports.
VDS has 1 year left on his Ajax employment contract. He was appointed CEO from the role as Marketing Director. VDS has been quoted on saying that he exepcts to return to the club in the future in some capacity.
I dont know what role excactly the club sees for Edwin, considering the roles he would be best suited for are currently occupied, but removing that obstacle, there are a lot of signs that point to VDS returning as a club executive.